M

EMO

Dean of

Graduate

Studies

ST

R

EET

A

l>

l>lt

ESS

Maggi

e Benston

Student

Services

Cent

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e

1100

Burnaby

BC

VsA

1

So

Canada

M A II. INC A I l I l

I

t

E

S

S

8888 University Drive

Burnaby

BC

VsA 1So

Canada

S.12-69

I

TO Senate

I

TEL

I

FROM

W

ade

Parkhous

e

,

D

ean,

Graduate Stud

i

es

~\?~~

I

RE

Fa

c

ulty

of

H

ealth Sciences

[GS2012.16)

I

CC

Mar

g

o Moore

I

DATE

7 M

a

r

c

h

2012

For information:

Acting

und

e

r

delegated

a

u

t

h

o

ri

ty a

t it

s

m

eeting of

5 March

2012

,

t

h

e

SGSC

moved

t

o

approve

th

e

following curriculum

r

ev

i

s

i

o

n

s:

Effective

Date is September 2012

Faculty

of Health

Sciences

!GS2012.16]

C

r

oss

-li

st

in

g

FHS

co

ur

ses

w

ith

Mo

l

ec

ul

a

r

Bio

l

ogy an

d

Biochemi

s

try

:

i

)

New

co

ur

ses:

H

SC

I

726

-

4

The Immune

System

1:

Ba

s

i

s of

Inna

te

and

Adaptive

I

mm

uni

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HS

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I

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Senators

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g to

consult a

m

ore

detailed report

of c

u

n

.i

cu

lum re

vis

i

o

n

s

may

do

so

b

y go

ing

to Docushare:

http

s

:

//

docushare

.

sf

u.c

a/

d

s

web

/

View

/

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ction-

12682

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pl

ease ca

ll

778

-

782

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3168

or

ema

il

s

helley

gai

r@sf

u

.c

a

.

SIMO

N

FRAS

E

R UN

I

VERS

I

TY

ENGAG

I

NG

THE WORLO

---

SIMON FRASER UNIVERSITY

THINK

I

NG

OF THE

WORLD

FACULTY OF

HEALTH

SCIENCES

Simon

Fraser University

Blusson

Hall

8888

University

Drive

Burnaby

,

B

.

C

.

V5A

1S

6

February

20,

2012

TO:

FROM:

Dr

.

Wade Parkhouse

Dean Graduate

Studies

Margo Moore,

Associate

Dean, Education

Faculty

of Health

Sciences

Margo Moore

Associate

Dean

,

Education

Office

:

778-782-3441

Fax

:

778-782-5766

Email

:

mmoore@sfu

.

ca

SUBJECT:

New Graduate Courses in Faculty

of

Health

Sciences

Cross-listed

with Molecular Biology

and

Biochemi

s

try

Dear Dr.

Parklf

o

~

se

:

As

Dr. Scott,

the cha

ir

of the MSc PhD committee in FHS has discussed with you, FHS is

resubmitting their proposal for two new

grad courses,

HSCI

726-4 and

HSCI

727

-

3,

that will

be cross

-

li

sted

with two MBB

graduate

course

s

that

are

already on the books (MBB 726-4

and

MBB

727

-

3).

Please find attached a memo from Bruce Brandhor

s

t

,

Chair

of MBB,

stating

that the MBB Grad

Studies Committee

ha

s

approved of

thi

s

plan

.

The

addition of

these two

courses

will

complete

the plan between FHS

and

MBB for

cross

listing

its

undergraduate and

g

radu

ate

immunology

courses,

Immun

e

Sy

s

tem I (MBB/HSCI 426

and

.

n

ow

MBB

726)

Immun

e System

II

(MBB/HSCI

427 and

MBB

727)

~

Note

that there

are

v

extra

requirements of the

graduate students enro

ll

ed

in the

courses

.

The cross

li

st

in

g

wa

s

designed to make

it

po

ss

ible for faculty in

the

FHS immunology

group,

which

spans

both

MBB

and

FHS,

to teach

these core

immunolo

gy

course

s

.

Sincerely,

......-.7

/'J

A

A'

(:)

-

.

p

v

..__~

'-V:..,J

()

Margo Moore

---

MEMO

Ch

ai

r

's

O

f

f

i

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SB 8166

T

el

:

778

-

782-4627

Fa

x:

7

7

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of

m

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o

l

ogy

a

nd bio

c

h

e

mi

s

t

ry

ATTENTION

Margo Mo

o

r

e

,

F

aculty of Health

Scien

c

es

FROM

Bruce Br

a

ndhor

st

, Chair, MBB

TEL

RE

Cro

ss

l

i

st

in

g of

.

MBB/HSCI

cour

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es 426,726,427,727

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th

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eady

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co

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MBB

/

H

SC

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426 a

nd 4

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k

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h

ese

co

ur

ses

f

or cred

it

.

Th

e

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qu

ire

m

ents

f

o

r

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nd

727 a

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iffe

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e

nt

a

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ore

so

phi

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ti

ca

t

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d th

an f

or 4

26 a

n

d

4

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iU initi

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al

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ndar

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ev

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ion

s

o

f

MBB

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in

s

ur

e

that

s

tuden

ts ca

nn

o

t t

ake

it

fo

r

c

r

ed

it

in a

dd

ition to MBB

/

H

SC

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4

27 o

r HS

C

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727.

Cc:

Ed

ga

r

You

n

g,

A

ct

in

g C

hair

,

MBB

G

r

a

du

ate

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tu

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itt

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l

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llt\SLR U:>:JVE

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H

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NKIN

G

OF

THE

WOR

LD

---

SIMON

FRASER

UNIVERSITY

DEAN OF GRADUATE STUDIES

FEB 2

1 2012

New

-.PROP

OSED

COURSE

DEAN OF GRADUATE

S·T·U~I~S fjf':f=l~

Program leg.

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Th

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Immun

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1

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Short Title

(appears on

transcripts,

max

25 characters)

Th

e

I

mmune

System

I

Course

Description

for SFU Calendar

0

see attached document

0

Learning outcomes

identified

The basic

orga

ni

zatio

n

of

the

immune system, includ

in

g s

t

ructure, function and genetics of antibodies, T

-

cell

receptors

,

innate

immune

re

cep

tor

s,

and the

comp

l

ement system.

Inn

ate, a

nt

ibody a

n

d ce

llular im

mune

r

esponses a

n

d

their

control, and

deve

l

op

ment

of

th

e ce

ll

s

involved

in th

ese responses.

Prerequisite: MBB 331

or

pe

rmission

of

the

in

st

ru

c

t

or. S

tud

e

nt

s

with

c

r

ed

it

for

MBB

or

HS

C

I

426,

MBB

826 o

r

MBB

726 may

not

co

mplete HSCI

726

fo

r

credit.

Available

Course Components:

IZJ

Lecture

121

Seminar

CJ

Laboratory

0

Practicum

0

Onl

i

ne

D

Grading Basis

l2l

Graded

D

Satisfactory

/Unsatisfactory

0

In Progress/Complete

Prerequisites

(if

any)

0

see

attached

docum

en

t

MBB 331 or permission of the instructor

.

0

This

proposed course

i

s

combined with an undergrad course: Course number

and

units:

HSC

1

4264

and

MBB

4264

Addit

i

onal course

r

equirements for

graduate

stude

nt

s

0

See attached docume

nt

(if

th

i

s s

pac

e

i

s

in

s

ufficien

t

)

An

ex

t

r

a

hour

of

tutoria

l

per

week

.

Campus at which course will

be

offered (check a

ll

that

apply

)

IZI

Burnaby

0

Vancouver

CJ

Surrey

O

GNW

D

Estimate

d

enrolment

I

Date

of

initial offering

I

Course delivery leg. 3 hrs/week for

13 wee

ks)

15

-

20

Fa

ll

20

1

2

4

h

r

s/week fo

r 13

weeks

Justifica

t

i

on

0

See

at

t

ac

h

e

d

document

-.RESOURCES

If

additional resources

are

required

t

o offer

thi

s

course

,

the departm

e

nt proposing

t

he course should be prepared to

provid

e

information

on the

so

urce(

s

) of

those additional

r

eso

u

rces.

Faculty

member(s) who

will

normally t

eac

h

this course

0

information

a

bout their

compe

t

ency

to

tea

ch the

course is appended

Jamie Scott (F

H

S &

MBB)

Number

of additional

fa

c

ulty

members required in order to offer this

co

ur

se

none

Additiona

l

space required in order

to

offer this course

D

see

atta

ched

d

ocume

nt

none

Additional specialized equipment required in

order

to

offer

this

course

O

see

attached document

non

e

Additional

Library

resources

required

(append details)

D

Annually$

D

One-time$

n

o

n

e

---

/

--PROPOSED

COURSE

from first page

Program

leg

.

ECON)

HS

C

I

j

Number leg.

81 0)

726

I

Units leg.

41

4

Course title

!max

80

characters)

Th

e

Immun

e Sys

tem 1

:

Basis

of

Inn

ate

and

Adaptive

lmm

u

-.APPROVAL

SIGNATURES

When a

department proposes a new

course

it

must first

be

sent

to

the chai

r

s of each

faculty

graduate program

committee

where there might be an

overla

.

p in

course content.

The

chairs

will

i

ndicate

that

overlap

conce

rn

s

have

been dealt with

by signing the appropriate

space or via

a

separate

memo or

e-mail

!

attached to this form).

Th

e

new

course proposal must

also be sent

to

the Library fo

r

a

report

on library resources.

Once

over

l

ap concerns

have been

d

eal

t

w

i

th,

s

ignatures

indi

cate approval

b

y

th

e

departmen

t

,

home fac

ul

ty and

Senate

Graduate

Stud

i

es Committee.

Other Faculties

The signature(s]

below indicate that the Dean(s]

or

designate

of other Faculties affected by the

proposed

new

course

suppor

t

!sl the approval

o

f

the

new

course.

Name of

Faculty

Signature

of Dean or Designate

Date

see attached

Dep

a

rtmental Approval

!non-departm

e

ntaliz

e

d

faculties

need not

s

ign]

Department Gradua

t

e Program Committee

S

ignature

Da

te

---

Department Chair

Signature

Da

te

Faculty Approval

Faculty

approval

indi

cates

that all the nece

ssa

ry

course co

n

te

n

t and ove

rl

ap

con

ce

rns

have been resolved, and

that

the

Faculty/Department

commits

to providing the required Library

f

und

s and any other necessary resources.

Faculty Graduate Program Committee

H

kft.

~

tJ

~

0

i)

,

ll. ..

A3,

Signature

)·

~

Senate Gradu

a

te Studies Committee Approval

Da

te

}

1

(':A

"2

v

"2o!

L

SGSC app

ro

va

l

ind

i

cates

that the

Libra

r

y

r

epo

rt

has been

seen, and

all

resource

issues

d

ea

lt

with. Once approved, new

cou

r

se

proposals

are sent

to Senate for

i

nformation.

Senate

Graduate Studies Comm

i

ttee

~

?GL<C'

~......_.

~

(\

-.CONTACT

Upon

approval of the course,

the

Dean of Graduate Studies office will

cons

ult

with

the

department or school regarding

other

co

ur

se a

tt

rib

ut

es

that may

be

required to

enab

l

e

the proper

entry of

the new

course

in the

student record system.

Department

I

School

I

Program

Co

nt

act

name

Contact emai

l

---

Instructor:

Descriptio

off opics

Grading:

Required texts:

Prerequisite:

Notes:

FACULTY OF HEALTH SCIENCES

HSCI

726-4

Immune System I: Basis of Innate and Adaptive Immunity

Fall2012

Dr. J. Scott, Office: SSB 7144 and BH 9706; Email: jkscott@sfu.ca

General Course Description

This course covers basic organization of the immune system, including structure, function

and genetics

of antibodies, T -cell receptors, innate immune receptors, and the complement

system. Innate, antibody and cellular immune responses and their control, and

development

of the cells involved in these responses.

3 lecture hours/week; 1 tutorial hour/week;

0 lab hours

Lecture Topics

1. Basic concepts in Immunology

2. Innate Immunity I

3. Innate Immunity

II

4. Antigen Recognition by B-and T-Cell Receptors

5. The Generation

of Lymphocyte Antigen Receptors

6. Antigen Presentation

toT Lymphocytes

7. Signaling through Immune System Receptors

8. The Development and Survival

of Lymphocytes I

9. The Development and Survival

of Lymphocytes II

I 0. T -Cell Mediated Immunity

11. The Humoral Immune Response

12. Dynamics

of Adaptive Immunity

13. The Mucosal Immune

System

7 bi-weekly, non-cumulative exams, a 30-min, in-class presentation, homework, class

participation. The final exam will not be cumulative.

K.M. Murphy,

P. Travers and M. Walport.

Janeway's Immunobiology.

8th Edition. 2012.

Garland Publishing, ISBN: 9780815342434.

http:/ /www.garlandscience.com/product/isbn/9780815342434

Original research articles and review articles.

MBB 331

or permission of the instructor.

HSCI 726 and MBB 726 are cross-listed courses; their content is identical. As compared to

their undergraduate counterparts taking HSCIIMBB 426, graduate students taking

HSCIIMBB 726 will present a primary paper from the literature on their own, and they are

expected to provide a longer summary that will include a literature review and a critique

of

the paper in light of the current literature. Students who have taken MBB 426, HSCI 426

or MBB 726 may not receive credit for HSCI 726.

Students requiring accommodations as a result of a disability should contact the Centre for Students with Disabilities

(778-782-5630 or e-mail: csdo@sfu.ca).

All students are subject to and responsible for being familiar with the

SFU academic integrity policy, which can be

found on-line at http://students.sfu.ca/academicintegrity/index.html

Students are expected to be familiar with the plagiarism tutorial found at

http://www-old.lib.sfu.ca/researchhelp/tutorials/interactive/plagiarism/tutorial/table-of-contents.htm

For help with writing, learning and study strategies please contact the

Student Learning Commons at

http:/ /learningcommons. sfu.ca/

---

FACULTY OF HEALTH SCIENCES

HSCI 426-4 The Immune System

1: Basis of Innate and Adaptive Immunity

Instructor:

Description/topics:

Grading:

Required texts:

Also Required:

Recommended texts:

0100 Fall2011

Dr. J. K. Scott, Office: SSB 7144 & BLU 9502; Email: jkscott@sfu.ca

General Course Description:

This course covers basic organization of the immune system, including structure, function

and genetics

of antibodies, T -cell receptors, innate immune receptors, and the complement

system. Innate, antibody and cellular immune responses and their control, and

development

of the cells involved in these responses.

4 lecture hours/week; 1 tutorial hour/week; 0 lab hours

Lecture Schedule:

Lecture#

1-2

3-4

5-6

7-8

9-10

11-12

13-14

15-16

17-18

19-20

21-22

23-24

25-26

Lecture#

1-2

3-4

5-6

7-8

9-10

11-12

13-14

15-16

17-18

19-20

21-22

23-24

25-26

Lecture#

1-2

3-4

5-6

7-8

9-10

11-12

13-14

15-16

17-18

19-20

21-22

23-24

25-26

7 bi-weekly, non-cumulative exams, one 15-min. in-class presentation, a 2-page

presentation summary, clicker quizzes. The final exam will not be cumulative.

K.M. Murphy.

Janeway's lmmunobiology.

8th Edition. 2011. Garland Publishing, ISBN:

978-08153-4243-4. http://www.garlandscience.com/textbooks/9780815342434.asp

!<Clicker (old and new ones are available

in the SFU bookstore)

Those interested

in medicine might like to get the companion text: R. Geha & F. Rosen.

Case Studies in Immunology.

5th Ed. 2007. Garland Publishing, ISBN13: 978-08153-

4145-1. http://www.garlandscience.com/textbooks/081534145l.asp

Prerequisite/co-requisite: Prerequisite: MBB

331 or consent of the instructor.

Notes:

Students who have taken MBB 426, BICH 426, MBB 726, HSCI 325, HSCI 425 or

HSCI 726, may not receive credit for HSCI 426.

Students requiring accommodations as a result

of a disability should contact the Centre for Students with Disabilities

(778-782-5630

or e-mail: csdo@sfu.ca).

All students are subject to and responsible for being familiar with the SFU academic integrity policy which can be found

on-line at http:/ /students.sfu.calacademicintegrity /index.html

Students are advised to review the plagiarism tutorial found at http://www-

old.lib.sfu.ca/researchhelp/tutorials/interactive/plagiarism/tutorial/table-of-contents.htm

For help with writing, learning and study strategies please contact the Student Learning Commons at

http://learningcommons.sfu.ca/

---

Instructor:

MOLECULAR BIOLOGY AND BIOCHEMISTRY

MBB 426-4

The Immune System I: Basis of Innate and Adaptive Immunity

Fall2011

Description/topics:

Dr. J. K. Scott, Office: SSB 7144 & BLU 9502; Email: jkscott@sfu.ca

General Course Description:

Grading:

Required texts:

Also Required:

Recommended texts:

This course covers basic organization of the immune system, including structure,

function and genetics of antibodies, T -cell receptors, innate immune receptors,

and

the complement system. Innate, antibody and cellular immune responses and their

control,

and development of the cells involved in these responses.

4 lecture hours/week; 1 tutorial hour/week; 0 lab hours

Lecture Schedule:

Lecture#

Topic

1-2

Basic Concepts in Immunology

3-4

Innate Immunity: The First Lines of Defense

5-6

The Induced Responses of Innate Immunity

7-8

Antigen Recognition by B-cell and T -cell Receptors

9-10

The Generation of Lymphocyte Antigen Receptors

11-12

Antigen Presentation toT Lymphocytes

13-14

Signaling through Immune System Receptors

15-16

The Development and Survival of Lymphocytes I

17-18

The Development and Survival of Lymphocytes II

19-20

T -cell Mediated Immunity

21-22

The Humoral Immune Response

23-24

Dynamics of Adaptive Immunity

25-26

The Mucosal Immune System

Chapters

1

2

3

4

5

6

7

8

8

9

10

11

12

7 bi-weekly, non-cumulative exams, one 15-min. in-class presentation, a 2-page

presentation summary, clicker quizzes. The final exam will not be cumulative.

K.M. Murphy.

Janeway's lmmunobiology.

8th Edition. 2011. Garland Publishing, ISBN:

978-08153-4243-4. http://www.garlandscience.com/textbooks/9780815342434.asp

!Clicker (old and new ones are available in the SFU bookstore)

Those interested in medicine might like to get the companion text: R. Geha & F. Rosen.

Case Studies in Immunology.

5th Ed. 2007. Garland Publishing, ISBN 13: 978-08153-

4145-1. http://www.garlandsciencc.com/textbooks/0815341451.asp

Prerequisite/co-requisite: Prerequisite: MBB 331 or consent of the instructor.

Notes:

Students who have taken BICH 426, MBB 726, HSCI 325 or HSCI 425 may not

receive

credit for MBB 426.

Students requiring accommodations as a result of a disability should contact the Centre for Students with Disabilities (778-782-5630

or e-mail:

csdoCtV.sfu.ca).

All students are subject to and responsible for being familiar with the SFU academic integrity policy which can be found on-line at:

http:!/students.sfu.ca/academicintegrity/index.html

Students are advised

to review the plagiarism tutorial found at

http://www-old.lib.sfu.ca/researchhelp/tutorials!intcractive/plagiarism/tutorial!tablc-of-contents.htm

For help with writing, learning and study strategies please contact the

Student Learning Commons at: http:illearningcommons.sfu.ca/

---

SI

MO

N

F

R

A

SE

R

U

NIVERSI

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Y

DEAN

OF

GRADUATE

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New Graduate Course

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HSCI

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810)

727

Cou

r

se

T

i

tle

(max 80 characters)

Immune System II

:

Immune Respon

ses

in Health and Disease

Short

Title (appears

on transcripts,

max

25

characters)

The

Immune

System II

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FEB 2 1

2012

DEAN OF GRADUATE

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Course Description for SFU Calendar

0

see

attached

document

0

Learning outcomes identified

Th

e

immunologic response to

bacterial

, v

iral

a

nd

parasitic infections,

im

munological di

seases,

such as autoimmune

diseases

,

immunodeficiency

,

hyper

se

nsitivity rea

c

t

io

ns

(including asthma and allergy) and transp

l

antation-

r

ejection

reaction

s

.

l

mmunotherap

e

utic

s

and

vaccine

dev

e

lopm

e

nt. Pr

ereq

ui

s

ite

:

MBB HSCI

426

or permission

o

f the instructor

.

Students with

credit for

MBB

427,

HS

C

I

42

7

or MBB

727

may n

ot

complete

HSCI

727

for cred

it.

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Course Components:

IZI

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0

Seminar

0

Laboratory

D

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0

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426 or perm

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co

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undergrad course:

Course

number and

un

its

:

HSCI

427•

3

an

d MBB

427

•

3

Additional

c

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attached

document (if this

s

pace

is

insuff

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An extra

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se

will be offered !check

all

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apply)

liZI

Burnaby

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Surrey

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I Date of initial offering

I

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for

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3

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Justification

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If additional resources are

required to

offer

this

course

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the

departm

en

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course shou

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be prepar

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to

provide

i

nformation on

the

sourcelsl of

those

additional resources

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member(sl

who

will

normally

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information about

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teach

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course

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Number of additional faculty

member

s

required

in

orde

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of

f

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this

cour

s

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none

Additiona

l

space

required in

o

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offer this

course

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see attached document

none

Additional specialized

equi

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required

in

order to offer

thi

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course

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Additional Lib

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---

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PROPO

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When a

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chairs

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h faculty graduate

program

comm

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ttee where

t

here

might be

an

overlap in

course

co

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chairs will indicate that overlap concerns

have

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by signing the

appropriate space

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via a

se

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Once overlap concerns

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signatures indicate approval

by

the department,

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faculty

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Other Faculties

The signaturelsl below

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Senate Graduate Studies Committee Approval

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for information

.

\.

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Upon

approva

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of the

course

,

the Dean

of Grad

u

ate

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t

u

di

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office will consu

l

t

with the

dep

a

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tmen

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ot

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er course attrib

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s

t

hat may be req

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ai

l

---

Instructor:

Descriptio niT opics

Grading:

Required texts:

Prerequisite:

Notes:

FACULTY

OF HEALTH SCIENCES

HSCI

727-3

Immune System II: Immune Responses in Health and Disease

Spring

2012

Dr. J. Choy, Office: T ASC II 8008; Email: jonathan.choy@sfu.ca

General Course Description

Many diseases are caused by dysregulation of the immune system. This course will

examine the immunological mechanisms underlying human immunodeficiencies, HIV

infection, asthma and allergy, autoimmunity, organ transplantation, and cardiovascular

disease. Immune responses to cancer and cancer immunotherapy will also be discussed.

Lecture Topics

I. Evasion and subversion of host defenses by pathogens

2. Human immunodeficiencies

3. Acquired immunodeficiency

4. Allergy and hypersensitivity

5. Physiological induction and maintenance

of tolerance

6. Autoimmunity

7. Transplantation

8. Tumor immunology and immunotherapy

9. Immunological aspects

of atherosclerosis

2 non-cumulative exams

(30o/o each), one individual in-class presentation with written

summary

(30o/o), and class participation (10%).

;t?

K.M. Murphy, P. Travers and M. Walport.

Janeway's lllullullobiology.

8th Edition. 2012.

Garland Publishing, ISBN: 9780815342434.

http://www.garlandscience.com/product/isbn/9780815342434

Original research articles and review articles.

The cross-listed courses, HSCI/MBB 426

or HSCIIMBB 726.

HSCI 727 and MBB 727 are cross-listed courses; their content is identical. As compared to

their undergraduate counterparts taking HSCIIMBB 427, graduate students taking

HSCIIMBB 727 will present a primary paper from the literature on their own, and they are

expected to provide a longer summary that will include a literature review and a critique

of

the paper in light of the current literature. Students who have taken MBB 427, HSCI 427

or MBB 727 may not receive credit for HSCI 727.

Students requiring accommodations as a result of a disability should contact the Centre-for Students with Disabilities

(778-782-5630

or e-mail: csdo@sfu.ca).

All students are subject to and responsible for being familiar with the

SFU academic integrity policy, which can be

found on-line at http://students.sfu.ca/academicintegrity/index.html

Students are expected to be familiar with the plagiarism tutorial found at

http:/ /www-old.lib .sfu.ca/researchhelp/tutorials/interacti ve/plagiarism/tutoriaVtab le-of-contents.htm

For help with writing, learning and study strategies please contact the Student Learning Commons at

http:/ /leamingcommons.sfu.ca/

---

FACUL TV OF HEALTH SCIENCES

HSCI 427-3 Immune System II: Immune Responses in Health and Disease

0100 Spring 2012

Time:

Professor:

Office:

Email:

Phone:

Office hours:

Wed & Fri 8:30am - 1 0:20am

Dr. Jonathan Choy

TASC 118008

jonathan.choy@sfu.ca

778-782-8701

TBD

COURSE DESCRIPTION:

Burnaby campus: BLU9660

Many diseases are caused by dysregulation of the immune system. This course will

examine the immunological mechanisms underlying human immunodeficiencies, HIV

infection, asthma and allergy, autoimmunity, and organ transplantation. Immune

responses to cancer and cancer immunotherapy will also be discussed.

Lecture Topics

1. Evasion and subversion of host defenses by pathogens

2. Human immunodeficiencies

3. Acquired immunodeficiency

4.

Allergy and hypersensitivity

5. Physiological induction and maintenance of tolerance

6. Autoimmunity

7. Transplantation

8. Tumor immunology and immunotherapy

TEACHING FORMAT: There will be two 2-hour classes each week.

REQUIRED TEXT:

1. K.M. Murphy, P. Travers and M. Walport.

Janeway's lmmunobiology.

8th Edition. 2012.

Garland Publishing, ISBN:

9780815342434.

http://www.garlandscience.com/product/isbn/9780815342434

2. Original research articles and review articles

GRADING:

Two non-cumulative exams

One in-class presentation with written summary

Class participation

PREREQUISITES:

30o/o each

30°/o

10°/0

HSCI 426 or MBB 426 or permission of the instructor. HSCI 427 is identical to MBB 427

and students cannot receive credit for both courses.

IMPORTANT NOTES: The professor may make changes to the syllabus if necessary,

within Faculty/University regulations.

Students who have taken MBB 427 or HSCI 427 may not receive credit for MBB 727 and

vice versa.

II

---

Instructor:

Descriptio niT opics

Grading:

Required texts:

Prerequisite:

Notes:

MOLECULAR BIOLOGY AND BIOCHEMISTRY

MBB427-1

Immune System II: Immune Responses in Health and Disease

Spring 2012

Dr. J. Choy, Office: T ASC II 8008; Email: jonathan.choy@sfu.ca

General Course Description

Many diseases are caused by dysregulation of the immune system. This course will

examine the immunological mechanisms underlying human immunodeficiencies, HIV

infection, asthma and allergy, autoimmunity, organ transplantation, and cardiovascular

disease. Immune responses to cancer and cancer immunotherapy will also be discussed.

Lecture Topics

1. Evasion and subversion of host defenses by pathogens

2. Human immunodeficiencies

3. Acquired immunodeficiency

4. Allergy and hypersensitivity

5. Physiological induction and maintenance

of tolerance

6. Autoimmunity

7. Transplantation

8. Tumor immunology and immunotherapy

9. Immunological aspects of atherosclerosis

2 non-cumulative exams

(30% each), one individual in-class presentation with written

summary

(30%), and class participation (10%).

!~

K.M. Murphy, P. Travers and M. Walport.

Janeway's lmmunobio/ogy.

8th Edition. 2012.

Garland Publishing, ISBN: 9780815342434.

http://www.garlandscience.com/product/isbn/9780815342434

Original research articles and review articles

MBB 426/726 or HSCI 426; MBB 427/727 is identical to

HSCI 427 and students cannot

receive credit for both courses.

Students who have taken MBB 427 or HSCI 427 may not receive credit for MBB 727

and vice versa.

Students requiring accommodations as a result of a disability should contact the Centre for Students with Disabilities

(778-782-5630

or e-mail: csdo@sfu.ca).

Ail students are subject to and responsible for being familiar with the SFU academic integrity policy which can be found

on-line at http:/ /students.sfu.ca/academicintegrity/index.html

Students are expected to be familiar with the plagiarism tutorial found

at

http://www-old.lib.sfu.ca/researchhelp/tutorials/interactive/plagiarism/tutoriaVtable-of-contents.htm

For help with writing, learning and study strategies please contact the

Student Learning Commons at

http://learningcommons.sfu.ca/

---

S

IM

ON

FRA

S

ER UN

I

VERSIT

Y

DEAN OF GRAD

U

ATE STU

D

IES

.

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an

SFU

department or program to

request a

minor change to an

existing

graduate course.

A

f

ter appro

v

al

and

signature by

the

faculty graduate studies committee, this form

should

be

forwarded to the

Dean

of Graduate

Studies

for approval

by the Senate Graduate Studies Committee !SGSC). SGSC

will forward the approva

l

to Senate

for

information.

DEPARTMENT

D

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partment

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School

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Program

F

ac

u

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y of

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Sciences

I

Contact name

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y

nn

Kumpula

T

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email

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umpula

@sf

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Please

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ing

elements of

the

indicated g

r

aduate course:

0

Catalogue

number

D

Units

D

T

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0

Descr

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pt

i

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El

Other:

Pre requisites

IIBZD

CURRENT COURSE

-~

REVISED

COURSE

Please

complete

only

the

fields to be

changed.

Pl

ease

complete

only

the

fields

to

be

changed.

Program

(

eg.

ECONI

I

Number

(eg. 8101

I

~

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HSCI

807

Program (eg. ECONI

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HS

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807

Course title !ma

x

80

characters!

Course title

(max 80 characters]

r

esearc

hing health inequ

i

ties

researching

health

in

equ

it

ies

Short

title !appears

on transcripts, max 25 characters]

Short title !appears

on

transcr

i

pts,

max

25 characters!

health inequities

health

i

ne

quities

Course description for

SFU Calendar

0

see

attached

Course descripti

o

n for SFU

Calendar

0

see

attached

Critical examination of methodologies and methods

for research on

Critical examination

of methodolog

i

es and methods for

research on

health inequities

related

to class

,

race, ethnicity, gender and other

health

inequities related

to c

l

ass,

race, ethnicity, gender

and other

social

axes of marginalization and power. Covers a range

of

social axes of marginalizat

i

on

and power. Covers a

range o

f

disciplines (epid

emiology,

social sciences), methodologies

disciplines (epidemiology,

social

sciences), methodologies

(pos

i

tivist,

cr

i

tical,

feminist,

indigenous) and methods

(qualita

t

ive,

(positivist, critical

,

femi

nist

,

indigenous) a

n

d methods

(qualita

t

i

v

e

,

quan

ti

tative

,

actio

n-

oriented).

Em

phasis on causes of and solutions

quantitative,

act

ion-orie

n

ted).

Emphasis on

c

auses o

f

and so

l

utions

to

sys

temic

health

inequities.

P

r

e

r

equ

i

site:

HSC

I

802

and 803, o

r

to

systemic health i

ne

qu

i

t

i

es.

P

r

erequisite:

HS

CI 802,

803,

838

o

r

permission

of

in

s

tru

ctor.

permission of instructor.

Available

course components

D

Lecture

0

Seminar

Available course components

0

L

ect

u

r

e

0

Seminar

0

Laboratory

0

Practicum

ID

Onlin

e

0

D

Laboratory

0

Practicum

0

Online

0

Grading basis

!a

Graded

0

Satisfactory

I

Unsatisfactory

Grading

basis

El

Graded

0

Satisfactory

I

Unsa

t

isfactory

0

In Progress

I

Complete

0

0

In Progress

I

C

o

mp

l

ete

0

Prerequisites !if

any]

Prerequ

i

sites !

if

an

y

]

HSCI

802 and 803 or

perm

ission

of

instr

uctor.

HSCI

802

,

803

and

838 or

permiss

i

on of

instruc

t

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This

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combined

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course

.

D

Yes

0N

o

Th

is

is

combined w

i

th an

undergrad course.

0

Yes

0

No

Course

number and units:

Course number

and

units:

Additional

course requirements for graduate students

Additional course requirements

for graduate students

Dr

.

Margo Moo

re

, Assoc. Dean Educat

i

on

Faculty

graduate studies

comm

ittee

name

~

0

~a..c--'d-o

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~-=

Date

Senate graduate

studies

committee name

Signature

Da

t

e

---

Existing Calendar Language

HSCI 807-3 Researching Health Inequities

Critical examination of methodologies and methods for research on health inequities related to class, race,

ethnicity, gender and other social axes

of marginalization and power. Covers a range of disciplines

(epidemiology, social sciences), methodologies (positivist, critical, feminist, indigenous) and methods

(qualitative, quantitative, action-oriented). Emphasis on causes

of and solutions to systemic health

inequities. Prerequisite:

HSCI 802 and 803, or permission of instructor.