SiMON FRASER
MEMORANDUM
UNIVERSITY
S7
?
•SENATE
?
From .....
......ATEçQMM..TTEEONA.CAMIC
PLANNING
Subject ......PROPOSED UND
?
GRAM
N
?
Date
..........P
ECEMBER .
18, .19.75
-- CLINICAL CHEMISTRY
?
MOTION: ?
"That Senate approve and recommend approval to the
Board of Governors the proposed program in Clinical
Chemistry as set forth in S76-
10
including:-
general regulations for a major program and an honors
program and proposed new courses CHEM 397-15, 398-15,
399-15, 420-3, 423-3, 424-2."
.
0
SiMON FRASER UNIVERSITY
?
MEMORANDUM
SENATE
From...........
SENATECOMM..TT!.E....ONACA.P.0
?
?
PLANNING ?
-
Subject ..............
CI4N ICAL1ISTRY
I
?
Date
........... DECEMBER
,..1$..,. ..... 19.7.5 ........... . ................... ..............
Action taken by the Senate Committee on Academic Planning
at its meeting of December 17th, 1975 gives rise to the following
motion:
nc'mTr y
T
1
That Senate approve and recommend approval to the
Board of Governors of the proposal for a program in
Clinical Chemistry as set forth in SCAP 75-4 revised.
There was considerable discussion within the Senate
Committee on Academic Planning regarding the assignment of
credit to the three clinical chemistry practica ( Chemistry 397,
398, and 399). While a number of alternatives were considered,
the consensus of the Senate Committee on Academic Planning was
that the Clinical Chemistry Training Program experience most
10
closely resembled the Professional Development Program in the
Faculty of Education and that, therefore, credit should be
assigned in an analogous manner. It is thus recommended that
each of the three Clinical Chemistry practica be assigned credit
of fifteen semester hours. Because of the specialized nature
of the practica, it is also recommended that credit for the
practica not be transferred to other degree programs in the
University.
.
1
'
December
1975
CLINICAL CHEMISTRY PROGRAM PROPOSAL
Outline
1.
Clinical Chemistry Program Proposal
Background
Proposal
Approach
Entrance
Program Operation
Program Objectives
Program
2.
New Course Proposal Forms and Outlines
• 3.
Estimates of costs for Clinical Chemistry Program Operation
4. Duties of Proposed Appointee in Clinical Chemistry Involving
Practicum (Chem
397-8-9)
Prepared By
Dr. A. C. Oehlschlager, Associate Professor,
Department of Chemistry, Simon Fraser University
and
Dr. R. A. Rockerbie, Clinical Chemist, Vancouver
General Hospital
.
.
- ?
2
CLINICAL CHEMISTRY AT S.F.IJ.
.
?
A PROPOSAL
Background
Clinical chemistry has been developing rapidly as a
vigorous specialty in Canada. The growing importance and
complexity of the service provided by the clinical chemistry
laboratories has aroused interest in establishing standards
of education and training that will insure competence in those
responsible for the practice at the patient-care level. A
survey was recently made of clinical chemistry training avail-
able at and beyond the B.Sc. level in Canada. In some areas
programs are well-developed and operational; in others, they
are in the planning stages; and in still others, they are non-
existent.
C
Canadian Programs in Clinical Chemistry(CC) and Medical
Laboratory Sciences (MLS) (B.Sc. and Higher)
University
?
Level
?
*11
University of Alberta (MLS)
B.Sc.
Lakehead University (MLS)
B.Sc.
University of Toronto
?
CC
PostDoctoral-
University of Windsor
?
CC
Ph.D.
University of Montreal
B.Sc.
McGill University (CC)
?
Ph.D, postdoctoral
McMaster University (CC)
Ph.D.
Univ. of Western Ontario (CC)
postdoctoral
University of Ottawa
?
(CC)
postdoctoral
Univ. of Saskatchewan (MLS)
B.Sc.
University of Waterloo (MLS)
B.Sc.
operational
operational
operational
operational
planning
planning
operational
planning
planning
operational
operational
Training
programs
in British Columbia
fall
in
?
the latt;er
category.
?
At
the
1974
Annual Meeting of
IUPAC,
endorsement was
-2-
C
C
given to the teaching of clinical chemistry in chemistry
departments.
Much of the current
?
need for Medical
.
Laboratory
Technologists is met by personnel trained in two year programs.
In British Columbia. training in Medical Laboratory Technology is
to the 2 year level, undertaken by a number of approved and
accredited hospitals in cooperation with the B.C.I.T. and
Cariboo College. In practice a. grade XII graduate enrolls in
the Medical Technology program at B.C.I.T. or C.C. After one
successful year of formal training equivalent to senior matricu-
lation the student applies for sponsorship to an approved hospi-
tal. If sponsored, the student completes one further year at the
educational institution and proceeds to one year of practical
hospital training. After a successful hospital training period
candidates are eligible to write the C.S.L.T. (Canadian Society
of Laboratory Technologists) examinations. These examinations
are multifaceted in that they test the candidates expertise in
hematology, clinical microbiology, histology, clinical chemiS-
try and blook bank technology. Successful completion of these
examinations leads to the professional qualification of Regis-
tered Technologist with what is termed a General Certificate.
A survey of B.C. hospital and private laboratories in
1974
indicated
.
a need for persons specializing in the area of
Clinical Chemistry. The provincial need for such trainees is
currently estimated at ten per year and is barely met by recruit-
ment from outside the province, training B.Sc. chemists and bio-
.
- ?
4
-3-
chemists and upgrading qualifications of technologists with two
0
?
year's formal training.
Refresher courses in clinical chemistry, sponsored by
the Education Committee of the B.C. Society of Medical Tech-
nologists during both
1973
(held at BCIT) and
1974
(SF11 as
host) were highly successful and well attended by practising
laboratory technologists.
The provincial government stated its intention to aid the
development of teaching facilities in the health-care field.
They have also urged provincial universities to evaluate their
offerings in terms of the needs of society for university gradu-
ates.
Proposal
•
It is proposed to initiate aprogram leading to a B.Sc. in
chemistry with concentration in the area of clinical chemistry. It
is proposed that courses in this area of concentration be avail-
able at times convenient to practising laboratory technologists so
that they may form part of a continuing and advanced education
program.
Persons completing the proposed option would be eligible
to write the CSLT examination in Clinical Chemistry, the suc-
cessful completion of which would qualify them for Subject
Certification. That is, they would have specialist qualifications
in Clinical Chemistry with respect to their two-year trained col-
leagues who have general qualifications. In addition the clinical
chemistry courses in this program would be of valuetopractising
• ?
technologists in their academic preparation for Advanced Registered
Technologist Certification examinations.
5
.
Approach
Course
Course offerings in Chemistry, Biosciences, Biochemistry,
Kinesiology, Mathematics, Physics, and Computing Science at
S.F.U. have been examined with a view toward development of an
undergraduate programwith concentration in Clinical Chemistry.
This examination led to the formulation of a core of courses
which were considered necessary for the graduate to meet for the
requirements proposed by Committees on Education in Clinical
Chemistry (CSCC). In addition to existing university courses, it
was considered essential to include two new lecture and one new
•
?
laboratory course in the specific area of clinical chemistry.
Entrance
Because of the need for concurrent theoretical and prac-
tical training we recommend that only those applicants be aLlowed
to enter this program who are able to be placed in teaching
hospital laboratories during the coure of their studies.
it is recommended that this requirement be waived for those stud-
ents with one year of similar laboratory experience.
The proposed mechanism of entrance is as follows:
• ?
1. ?
The student applies to SFU and is accepted into the
University.
(
2. ?
Student completes first years of basic science courses
(per typical program outline) and applies for admission
into Clinical Chemistry Program to Crernistry Department
__ •
? • ••.
-5-
?
3. ?
Chemistry Department, with Hospital personnel (Advisory
Board), select students to be admitted. At this time
•
?
provision for hospital training is made.
?
. ?
Students admitted go forwards
Proaram Operation
It is proposed to establish an advisory board to oversee
the operation of this program. Membership should be distributed
between the university departments contributing major numbers
of courses, (Chemistry, Biosciences, Kinesiology) and the hospi-
tal laboratories involved in the off-campus training. The
advisory panel should be involved in curriculum review and coor-
dination of the hospital training. This latter function
will involve selection and placement of students in approved
laboratories.
Program Objectives
To prepare the Clinical Chemistry Proram graduate with the
following abilities:
1.
Work independently in the clinical chemistry laboratory.
2.
Read, understand, develop, and standardize methods for
routine laboratory use.
3.
Understand all phases of clinical chemistry labora-
tory operation.
k. Monitor quality control.
5. Troubleshoot a method and spot potential errors.
6;
Understand data reduction and dissemination.
7.
Understand the physiological significance of the data.
8.
With guidance, aid in the training of technicians and
technologists in methods of analysis.
.
- ?
7
9.
Understand the fundamentals of instrumental design, opera-
tion, and methodology as used in clinical chemistry labora-
tories.
10.
Assist the laboratory director in carrying out research
projects.
Program
A Major and an Honors Program in Clinical Chemistry is offered
by S.F.U. through the Department of Chemistry. This program
is designed so that the student will be eligible to write the
Subject Registered Technologist Certification Examination in
Clinical Chemistry concurrent with obtaining the B.Sc. degree. This
Program is also available to interested medical laboratory tech-
nologists who wish to pursue their studies in such a way that
they will be eligible to write the Subject Advanced Registered
Technologist Examinations in Clinical Chemistry concurrent with
.
?
obtaining the B.Sc. Because of the requirement of the Canadian
Society of Laboratory Technologists that a student train in an
approved laboratory for one year as a partial requirement for
an R.T., each student without prior hospital laboratory exper-
ience, will be required to train in an accredited hospital labora-
tory normally in one semester of each of the second, third and
fourth year of study. Students may be admitted to the B.Sc.
Clinical Chemistry Program with advance standing. Transfer credit
may be granted for appropriate academic work completed at other
institutions to a maximum of 60 semester hours excluding hospital
training or 105 hours including acceptable hospital laboratory
training (an accepted equivalent of Chem
397, 398,
399).
S
- ?
8
-7-
The courses required of students in the Clinical Chemistry
Program who have had no previous post secondary training are:
Biochemistry:
?
301-3 ?
The Structure and Reactivity of Biomolecules
?
302-3
?
Metabolism
?
311-2
?
Analysis of Biomolecules Laboratory
?
312-2
?
Metabolism Laboratory
Bioscience:
101-4
Introduction to Biology
102-4
303-3
Microbiology
428-3
Experimental Techniques I
• Chemistry:
104-3
General Chemistry I
105-3
General Chemistry II
115-2
General Chemistry Laboratory
117-2
Quantitative Chemistry Laboratory
233-2
Inorganic. Chemistry of Biological Processes
251-3
Organic Chemistry I
252-3
Organic Chemistry II
256-2
Organic Chemistry Laboratory I
397-15,398-15,399-15
Hospital Training
16-3
Modern Methods of
Analytical Chemistry
20-3
Clinical
Chemistry I
423-3
Clinical
Chemistry II
424-2
Clinical
Chemistry Laboratory
a
0
Computing Science:
-8-
105-3
Kinesiology:
100-3
336-3
)405-3
'to6-3
k07-3
Introduction to Concepts and Procedures
Introduction to Concepts and Procedures
Microscopic Anatomy (Histology)
Human Physiology I
Human Physiology II
Hunan Physiology Laboratory
Mathematics:
101-3 -Introduction to Statistics
?
151-3 ?
Calculus I
?
152-3
?
Calculus II
?
302-3
?
Statistical Methods
Physics:
101-3
?
General
Physics I
102-3
?
General Physics II
3331 ?
Introduction to Instrumentation in the Life
Sciences
Total semester hours= 10
-10
.
In addition to these courses students pursuing the
Clinical Chemistry
Program
must complete additional university
B.Sc. requirements. For the Major
Program
these requireinertt
involve
the completion of an additional 25 semester hours of
electives
Applicants for
admission to
the Honors
Clinical Chemistry
Program
will normally
be expected
to achieve
a cumulative Lrrade
average of B in post secondary courses. The University
requires that a student maintain this standard to continue in
an Honors
Program.
In addition to the courses listed above students pur-
suing the
Clinical Chemistry
Honors
Program
must
complete
an
additional
37
semester hours
of course work
( ?
177
total)
toinclucie:
Biochemistry: ?
411-2 Enzymology Laboratory
Bioscience: ?
401-3
Biochemistry II
'405-3
Cell Physiology
Chemistry: ?
341-3 Radiochemistry
and either Chemistry
481-5
or Biochemistry 491-5.
.
11
-10-
S
Typical Program Outline
First Year (27)
Biosci
10114,
102-4
Chem
104-3,
105-3,
?
115-22 ?
117-2
Math
101-3,
151-3,
?
152-3
Second Year
?
(ko)
Chem
233-21
251-3,
?
25 2
-3, ?
256-2, ?
397-15
Comp Sci
105-3
Phys
101-3,
102-3
Kines
100-3,
336-3
Third Year (41 '
Biochem
301-3,
?
302-3,
?
311-2,
?
312-2
Biosci
303-3
Chem
398-L5
Kines
05-31 ?
1
4063,
?
407-3
Phys
333-4
Fourth Year
(32)
Biosci
?
428-3
Chem
?
416-3, 420-3
1
423-3, 424-2,
399-15
Math ?
302-3
S
.
-
?
12
-11-
Special Instructions for Clinical Chemistry Hospital Trainin
397, 393,
and 399
1.
Students must complete normal University registration pro-
cedures and be admissible to the University before enrol-
ing in Clinical Chemistry
397, 398,
or
399.
It is highly
recommended that such students complete their University
registration sixty days in advance of the commencement of
the semester in which they plan to enrol in these courses.
In addition, students desiring to enrol in these courses
must make written application to the Chemistry Department
at least sixty days before the commencement of the semes-
ter in which the course commences. Later applicants will
be considered only if space is available.
2.
In the event that the number of applicants to Clinical
Chemistry
397, 398,
and
399
exceeds facilities and staff-
ing capabilities, the Clinical Chemistry Admissions
Committee will select those applicants considered to be
the best qualified.
3.
Students who have indicated their intention to undertake
a given semester of Clinical Chemistry
397, 398
or
399,
and who do not honor this commitment, are considered to
• ?
re-enrol in Clinical Chemistry Hospital Training courses
is not given automatically. Such permission must be
by written request from the student to the Chemistry
Department
3
months prior to the start of the semester in
which the student proposes to re-enrol in these courses.
k.
Students may request or be required to discontinue studies
in Clinical Chemistry Hospital Training. A refund schedule
for students withdrawing from Chemistry
397, 398,
and
399
will parallel that approved from time to time by the Board
of Governor
snAt)e
q,.
5.
Clinical Chemistry
397, 398,
and
399
are considered full
time professional studies and may not
normally be taken in conjunc-
tion with other academic or professional courses ___
4QC
-Ii ?
,-c.
?
(i
?
_____
tt41
1
M4..'
&4
€4
4
ti,)
. ?
S
.
- ?
13
-12-
SENATE COMMITTEE ON UNDERGRADUATE STUDIES
NEW COURSE PROPOSAL FORM
Department:
Chemistry-.
Calendar Information
?
397
Abbreviation Code:C1M Course Nuer:
397
?
Credit Hours:
15.
Vector:
Title of Course:
Clinical Chemistry Hospital Training
Calendar Description of Course:
Full-time practical experience in approved
Ospital laboratories in the use of chemical diagnostic tests.
training
(Credit for this course
sferable to
is
other
not
degree
h
tran
programs
at S.F.U.)
Nature of Course
Prerequisites (or special instructions):
Chem 117 or Permission of the Department of Chemistry
What course (courses), if any, is being dropped from the calendar if this
course is
approved:
None
2. Scheduling
?
How frequently wi].1 the course be offered?
?
Every semester
Semester in which the course will first be offered? Fall
1976
Which of your present faculty would be available to make the proposed offering
. possible?
None
3.
Obiectives of the Course
To give the student practical clinical laboratory experience in
approved laboratories and to meet Canadian Society of Laboratory
Technologists
in clinical Chemistry.
requirements for Registratio
n
as a medical
me
?
flologiSt
4.
BudgetarY and Space Reguiremen
?
(for information only)
What additional resources will be required in the following areas:
Faculty
A SFU employed coordinator will be required*.
Staff Nil
Library Nil
Audio
Visual
Nil
Space
?
Nil
Equipment Nil
?
* Same person as instructing Chem
?
423
and 424.
5.
A
2kEoval
Date:
• ?
Dertment
___
Chairman
?
Dean
Chairman,
SCIJS
Memorandum
SCUS
73-34a.
SCUS 73-34b:- (When completing this form, for instructions see
-13-
SENATE COMMITTEE ON UNDERGRADUATE STUDIES
.
NEW COURSE PROPOSAL FORM
1. Calectdnr Information
Department:
Chemistry
Abbreviation Code:CHEM
?
Course Number:
398
?
Credit Hours;
1
5
Vector:___
Title of Course:
Clinical Chemistry Hospital Training
Calendar Description of Course:
Full-time practical experience in approved training hospital laboratories.
in the use of chemical diagnostic tests.
(credit foiz this course is not transferable to other degree programs
at S.F.U.)
NAture
of
Course
Prerequisites (or special instructions):
Chem
397
or permission of the Chemistry Department
What course (courses), if any, is being dropped from
the calendar if this
course is
approved:
None
2.
Schedulil!A
How frequently will the course be offered?
Every semester
Semester in which the course will first be offered?
Fall
1976
. ?
Which of
your present faculty would be available to
make the proposed offering
possible?
None
3.
Objectives of the Course
To give the student practical clinical laboratory experience in
approved laboratories and to meet Canadian Society of Laboratory
Technologists requirements for Registration as a medical tecItnolOgiSt
in Clinical Chemistry.
4.
Budgetar
y
and Space Requiremeflt! (for information only)
What additional resources will be required in the following areas:
Faculty ?
A part time teaching appointee will be required"
Staff ?
Nil
Library
?
Nil
Audio Visual
Nil
Space
?
Nil
Equipment
Nil
* same person as instructing Chem
420, 423
and
k211
5.
Approval
Date:
Depment Chairman
?
Dean
?
Chairman, SCUS
SCUS
73-34b:-
(When completing this form, for instructions see Memorandum.
SCUSJ334a.1
.
44Ae.
Dean
DeWrtment Chairman
Chairman,
SCIJS
?
-
_14-
SENATE COMMITTEE ON UNDERGRADUATE STUDIES
?
NEW COURSE PROPOSAL FORM
a.
1.
Calendar Information
Abbreviation Code:
CHEM
Title of Course:
Clinical Chemistry Hospital Training
Calendar Description of Course:
Full-time practical experience in approved training hospital laboratories.
in the use of chemical diagnostic tests.
(Credit for this course is not transferable to other degree programs
at S.F.U.)
Nature of Course
Prerequisites (or special instructions):
Chem
398
or Permission of the Chemistry Department
What course (courses), if any, is being dropped from the calendar if this course is
approved:
None
2.
Scheduling
How frequently will the course be offered?
?
Every semester
Semester in which the course will first be offered?
Fall
1976
Which of your present faculty would be available to make the proposed of
possible?
None
3.
Objectives of the Course
To give the student practical clinical laboratory experience in
Approved laboratories and to meet Canadian Society of Laboratory
Technologists requirements for Registration as a medical technologist
in Clinical Chemistry.
4.
Budgetary and Space Requirements (for information only)
What additional resources will be required in the following areas:
Faculty
?
A
part time teaching appcintee will be required*
Staff ?
Nil
Library
?
Nil
Audio Visual
.
Nil
Space ?
Nil
Equipment
Nil
* same person as instructing Chem 420, 423 and 424
5.
Approval
Date:
// 4-,4
Department:
Cliemistry
Course Number:
399
?
Credit Hours:'
1
5
Vector:________
.
SCUS 73-34b:
—
(When completing this form, for instructions see Memorandum
SCUS 1334a.
16
CHEMISTRY
397,398,399
397,398, 399
COURSE OUTLINE
The laboratory training program is designed to allow
the student to gain practical experience in a functional
clinical chemical laboratory. This practical training will
supplement the theoretical courses (CHEM 420 and 423).
.
.
1/
SENATE COMMITTEE
COaTTEE
ON UNDERGRADUATE STUDIES?
NEW COURSE PROPOSAL FORM
OCaleidar Information
?
Department:
?
Chemiy
Abbreviation Code:
CHEM
?
Course Number:
420 ?
Credit Hours:
3
Vector:
3-10 -
Title of Course:
Clinical Chemistry I
Calendar
An introduction
Description of
to
Course:
the biochemical processes in the organs, tissues
and fluids of the human-body and the effect of disease on these pro-
cesses. Biochemical methods and laboratory diagnoses as applied to
the study of disease.
Nature of Course
Lecture Tutorial
Prerequisites (or special instructions):
Prerequisite: Third year standing in Chem or Biochem or permission
of department.
What course (courses), if any, is being dropped from
the calendar if this course is
approved
This is a course similar in content to Chemistry
420-3
offered
in
74-3
as an evening course.
2. Scheduling
How frequently will the course be offered?
once per year
Semester in which the course will first be
offered?
Fall
1976
Which of your present faculty would be available to
make the proposed offering
possible?
None
3.
Oblectives of the Course
To relate the principles of chemistry as they apply to the nature. and
detection of disease.
4.
Budgetary and Space Requirements (for information only)
What additional resources will be required in the following areas:
Faculty
?
An additional professional appointment will be requd*
Staff
?
Nil
Library ?
Nil
Audio Visual Nil
Space ?
Nil
Equipment
?
Nil
* Same person as instructing Chem
423, 424
5.
Approval
Date:.
• __________
De5iint Chairman
?
Dean ?
.
Chairman,
.
SCUS
ions see Memorandum
SCUS 734,
SCUS 73-34b:- (When completing this form, for instruct
/18
A
p
ob
?
.am
-17-
CHEMISTRY 420-3
COURSE OUTLINE
Topics
?
1 ?
--Course introduction, review of development, of clinical
chemistry
--Differentiation of health and disease, pathological
?
processes, concept of normal physiological ranges.
?
2 ?
--Quality assurance systems, reference materials, error
analysis.
--Specimen collection, handling and storage, deprotein-
izat ion
?
3
?
--Respiratory function and biochemical acid-base balance
--Disorders and assessment of acid-base equilibria
?
4
?
--Fluid and electrolyte regulation osmolality
?
5 ?
--Renal anatomy, biochemistry of urine formation
?
6 ?
--Assessment of renal function
--Anatomic considerations of the liver, bilirubin metabolism
?
8 ?
--Liver function tests and their role as diagnosti cs
?
9 ?
--Electrophoretic assessment of protein disturbances
--The immunoglobulins: classes, structure and function
--Immune mechanisms and deficiency states
?
10
?
--Biochemical disorders of carbo-hydrate metabolism
?
11. ?
--Lipids: methods of transport, inter-relationship with
carbo-hydrate metabolism
--Lipoprotein patterns in disease, cholesterol, tribycerides
?
12 ?
--Pancreatic secretions and malfunction in disease
--Biochemistry of the gastro-intestinal system and
assessment
--Malabsorption
?
13 ?
.
?
--The cerebrospina1 fluid. system
?
0
?
--Iron and magnesium metabolism, diagnostic implications
- ?
19
• ?
4
"
Ch
e6.
Dyrtmont Chairman
Dean
?
Chairman, SCUS
-18-
SENATE COMMITTEE ON UNDERGRADUATE STUDIES
?
NEW COURSE PROPOSAL FORM
• Calendar information
?
Department:
?
Chemistry
Abbreviation Code:
CHEM Course Number:
423
?
Credit Hours:
3
Vector:
310
Title
of Course: ?
Clinical Chemistry II
Calendar Description of Course:
A continuation of Chem
420-3
dealing with the nature and appraisal
of disease-affected systematic function; pharmacological and analitical
aspects of clinical toxicology; clinical laboratory systems.
Nature of Course
Lecture Tutorial
Prerequisites (or
special instructions):
Chem
420-3
or permission of department
What course (courses), if any, is being dropped from the calendar If this course Is
approved:
None
2.
Schedulin
g
How frequently will the course be offered?
Once per year
Semester in which the course will first be
offered?
Spring 1977
Which of
your present faculty would be available
to make the proposed offering
possible?
None
3.
Objectivesof the Course
To relate the principles of chemistry as they apply to the nature
and detection of disease.
4.
Budgetary and Space
-
Requirements (for information only)
What additional resources will be required in the following areas:
Faculty ?
An additional professional appointment will be required*
Staff ?
Nil
Library
?
Nil
Audio ViaualNjl
Space
?
Nil
Equipment ?
Nil
* same person as instructing Chem
420
and
424
5.
Approval
Date:
SCUS 73-34b:-
(When
completing this form, for instructions see Memorandum SCUS
7334a.
20
-1
9-
CLINICAL
CHEMISTRY
423-3
COURSE OUTLINE
k.
• Week ?
pics
1 ?
--Pathophysjoiogy of the thyroid gland: laboratory
ffldiri
in disease.
2
--Steroid
Pituitary
hormones,
and adrenal
biochemical
glands;
inter
-relationships of the
--Laboratory
assessment
of the P
ituita
r
y
-adrenal axis.
3
--Adrenal medullary
hormones.
--Porphyrjns:+ metabolism and measurement.
--Hormones of the
reproductive
system.
--Amino acids,
?
inborn errors of metabolism
6
--Diagnostic enzymology.
--Cardiac
Implications.
enzyme disturbances and thei
?
diagnuctj.c
•
7
--Principles of
ph
armacology,
?
classes of drug rL(ti()r
8
--Clinical
toxi
cology, drugs of abuse.
9
--Toxicological
analyses.
10
--Automated analyses, discrete sampling and
11
--Drug interaction in biochemical testing.
12
--Laboratory data Processing, and patterns or
13
--Clinical chemistry in Industrial and occup:jt,ion
fl]
?
Fe
- ?
21
-20-
SENATE COMMITTEE ON UNDERGRADUATE STUDIES ?
NEW COURSE PROPOSAL FORM
S
Calendar Information
?
Department:
Chemistry
Abbreviation Code:
CHEM
Course Number:
424
?
Credit Hours:2
?
Vector: 0-0-4
Title of Course:
Clinical
Chemistry Laboratory
Calendar Description of Course:
This course is designed to teach the principles used in the development
and assessment of analytical procedures for established diagnostic
tests; practical exercises in trouble-shooting of chemical methods will
be undertaken.
Nature of Course
Laboratory
Prerequisites (or special instructions):
Chem 398, Chem
420
or permission of department;
..
ordinarily taken with
Chem
423.
What course (courses), if any, is being dropped from the calendar if this course is
approved:
None
2. Scheduling
How frequently will the course be offered?
Once per year
Semester in which the course will first be offered?
Spring 1977
Which of your present faculty would be available to make the proposed offering
5
possible?
None
3.
Objectives of the Course
This course will enable the student to recognize and remedy the sources
of error in chemical diagnostic tests. It is also anticipated that
students completing the course will be equipped to independently
improve and/or introduce new diagnostic tests.
4.
Budgetary and Space Requirements (for information only)
What additional resources will be required in the following areas:
Faculty
An additional appointment will
be required*
Staff ?
1/4
time
Demonstrator
Library
Ni].
Audio Visual Nil
Space ?
Laboratory space for
20
persons is available
Equipment
5. rova
person as instructing Chem
420
and
423.
Date:
•
Depgf tiiñt Chairman
?
Dean ?
Chairman,,
S CUS
?
--
• ?
9
SCUS 73-34b:- (When completing this form, for instructions see Memorandum SCUS 73-34a.
-21-
CHEMISTRY ?
2'r
CC T
JRSE OUTLINi
Week
1
ColorimetriC determination of glucose in serum, and
systematic study of the effect of procedural variables.
2
Measurement of serum amylase activity with differ
substrates and assessment of precision, and correla-
tion of results.
3
Evaluation and comparison of a kinetic and
?
.:d-point
method for the quantitation of lactate dehyI'ogeflaSe
activity in serum.
4+5
Use of criteria for the systematic evaluation of test
procedure for the measurement of cholesterol iii serum.
6
Development of a procedure for the quantitation of urea
using p_dimethylamiflo_beflZa1dehY.
7
Error ?
detection in a troublesome procedure for the
measurement of urea in serum by the Berthelot reaction
8
Introduction of modifications to improve a procedure
for serum bilirubin quantitation
9
Assessment of test sensitivity for the detectiofl.o±'
hemoglobin and ketonic substances
io
Evaluation of serum
?
reference materials for use as
standards.
11
Student selection of a test procedure
12
for anendccrifle hormone on the basis of published
13
appraisals, followed by setting it up in the laboratory.
.
- ?
23
-22-
ESTIMATE OF COSTS FOR CLINICAL CHEMISTRY OPTION OPERATION
Personnel Required:
level (per AC16)
August
31,
1976
to achieve a close
provincial government
of Clinical Chemistry
Consultant - half time Faculty
January 1, 1976 -
This position is required
liaison with hospitals and the
for the funding and placement
training.
Appointments in Clinical Chemistry
-two half time faculty appointments (per AC16)
September 1, 1976 onwards
The duties of these appointments involve teaching
Chem
420,
4
23, 424
and liaison of the prac-
ticum as outlined in the attached.
Laboratory Technician - one fourth of full time Grade 8
or 9 technician is required per year to
maintain Chem
424
experiments.
Teaching Assistant - one 15hr graduate level teaching
assistantship will be required per year
for Chem
424.
Clerk Typist - one fourth of full time clerk typist
will be required to meet education material
preparation and liaison requirements.
Equipment:
Chemistry
424
will require four Coleman
2
visible spectro-
photometers (orequivalent)
?
$1000 each = $
4000.00
One additional recorder for available UV spectrophotometer
will be required ?
$1000.00
TOTAL EQUIPMENT
?
$5000.00
.
- ?
24
.
.
-23-
Materials and Supplies
Chemistry 424 will require glassware and chemicals costing
approximately ?
$3000.00
Advertising, promotion
?
$ 500.00
Travel expenses to B.C. Hospitals and Victoria
?
$ 500.00
TOTAL NON-SALARY REQUIREMENTS
?
$9000.00
.
- ?
25
-24-
.
.
DUTIES OF PROPOSED APPOINTEE IN CLINICAL CHEMISTRY INVOLVING
CHEM
397,
398,
399
1.
To promote good public relations with hospital-labora-
tories and such other institutions as may be involved
in the training of students.
2.
To liase with hospital laboratory administrators and
provincial government offices in connection with
wages or stipends for students while in training in
hospital laboratories.
3.
To jointly arrange a syllabus of instruction with each
training laboratory for the training of students
pursuant to the objectives of Chem
397-8-9.
The
syllabus will vary depending on the patterns of work-
flow within the specific laboratory, and on the indivi-
dual students prior experience.
k. To supervise the selection and placement of students for
training purposes in (CMA) approved laboratories.
5.
To co-ordinate, monitor and assess the progress of students
while in practicum training and to maintain records thereof.
6.
To advise hospital laboratories in the selection and
assignment of suitable laboratory exercises to fulfill
the requirements of the syllabus.
7.
To hold regular, probably bi-weekly, tutorials for these
students in the lower mainland, and to arrange for same
in other areas as needed.
8.
To act as a student councillor on matters pertaining
to the practical training.
.10
- ?
26
