SiMON FRASER UNIVERSITY
MEMORANDUM
SENATE COMMITTEE ON UNDERGRADUATE
From
?
SI1JDIES
.
To
SENATE
Subject
?
NEW COURSE PROPOSAL - CHEM 420-3 -
?
Date
?
APRIL 18, 1974
MOTION 1: ?
"That Senate approve, as set forth in S.74-51,
The new course proposal for CHEM 420-3 -
Clinical Chemistry."
MOTION 2:
?
"That Senate waive the normal two semester
time lag requirement in order that CHEM 420-3
may be first offered in the Fall semester 74-3."
s-
74-,5-1
The Senate Committee on Undergraduate Studies has exaidned the
attached new course proposal for Chemistry
20-3:
Clinical Chemistry and
recommends its approval to Senate. Should this approval be forthcoming,
the Caiirnittee further recommends that the normal two semester tine lag
be waived in order that this course may be first offered during the Fall
semester, 1974.
It should be noted that the offering of this course represents
movement into a new area for the Chemistry Department • However, it is
not anticipated, at this time, that this course should form the basis
for a new program, but rather a means of testing the acceptability of
such a course and the viability of the introduction of this area in the
Department's curriculum. Thus, in keeping with the first entry under
Section 2 of the course proposal form, the Senate Committee on Under-
graduate Studies recommends that the course be offered once and evaluated
before any subsequent offering.
ZL
I. Mugridge
ails
att.
40
SC.LA,
SiMON FRASER UNIVERSITY
MEMORANDUM
From
................
..S............. ............ )
?
Dean of Science
Date
....................
M3XCh26,1974
SenateCominitteeon
Subject
• ?
"Clinical Chemistry"
The Faculty of Science approved the attached new course proposal, CHEM 420-3,
"Clinical Chemistry", at its meeting of March 19, 1974. It is recommended
that this course be approved for an initial offering in 74-3.
1w ? .
Enclosures
cc: Chairman, Dept. of Chemistry
Ll
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YDwJC
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SiMON FRASER UNIVERSITY
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•.
MEMORANDUM
.....
..
.
From..T...
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N.
...............
Dean
Subect
...................................................... . .................... . ............ ........................
..D.p..rtmentof .
ç4y
........... ......................
Date ...
l,7.
h
t
December
1,9,7.3
.................... .........................
Please find attached course proposal, Clinical Chemistry,
which was approved by the Department at a meeting held on
FrIday, 7th December
1973.
It is Intended that the course be offered in the fall
semester
19714
with no further commitment at this time. Thus I
would be
,
grateful if you would deal with this proposal In the
immediate future in order that if approved through the various
committees, Senate approval can be obtained for a fall
19714
course mounting..
The Department is at this time carefully considering curriculum
development with a view to' extending its present offerings to areas
not encompassed in the present programs of B.Sc. chemistry, biochemistry,
chemical physics. We anticipate that by extending our offerings in
the chemistry majors program we can provide options with some
applied bias which would be not only of benefit to our own Internal
students, but potentially to off-campus persons.
The, feedback which should result from this particular
course will be of immense benefit to us in helping guide the
right kind of future development which the Department wishes
to undertake. Hence the requirement for mountingithis course
as soon as possible.
In order to teach this course we
.
would have to Use external
expertise, and thus require an appointment of a sessional lecturer
for this purpose. The man we would consider for this purpose is
Dr. R.A. Rockerbie of the Lions Gate Hospital. Irequest; that you
seek the necessary funding as a parallel action to considerations
for this course proposal.
T.N. Bell
End.'
TNB:rdh
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SENATE CO14ITTEE ON UNDERGRADUATE STUDIES
NLW COURSE PROPOSAL FORM
.1. calendar Information
?
Department:
Chemistry
W ?
Abbreviation Code:
Chem
Course Number:
420
?
Credit
Hours:_i_
Vector':
3-1-0?
Title of Course:
Clinical Chemistry
Calendar Description of Course:
An introduction to the biochemical processes
In
the
organs, tissues arid fluids of the human body and the effect of disease on
these processes. Bioóhemical methods and laboratory diagnpses as applied to the
study of disease.
?
.
?
.
Nature of Course
Lecture/Tutorial
Prerequisites (or special instructions):
Chem
252-3,
Chem
1
421_3
or
permission of 'Department
What course (courses), if any,
,
is being dropped from the calendar if this course is
approved:
?
None - Course' is an elective
2.
Schedulip
A.
'
Row frequently will the course be offered?
To be offered once and then evaluated.
Semester in which the course will first be o'erecrr
197-3
Which of your present facult
y
would be available to make the proposed offering
possible?
None
3.
Ob
j
ect
i
ves of the
Course-The
present core curriculum and 'choice of electives
'dc
?
not adequately prepare*
,the B.Sc. graduate in chemistry to be" o' practical
vaiue in the clinical laboratory
,
as it now operates within the hospital, public
health, or industrial environment. This course will provide the student with
exposure and some basic knowledge of the-health-care field
and will expand his field of competency generally.' Course outline attached.
4.
Budgetary and Space Requirements (for information on
What additional resources will be required in the following areas:,
Faculty' ?
Appointment of sessional lecturer
Staff'
Library ?
-
Audio Visual
Space
Equipment ?
-
5.
Approval
Date:
?
/( IL
73.
Depa mént Chairman
I'
De aff
Chairman, SCUS
SCUS 73-34b:-
(When completing this form, for instructions see Memorandum SCUS 73-34a.
Attach course outline).
?
.
Course Outline
?
•
?
?
The ?
following, list of topics are relevant to Clinical Chemistry.
A coherent set from these topics will be presented in this
course.
?
1.
?
Course introduction, review of development of clinical chemistry.
?
2'. ?
Differentiation of health and disease, pathological processes,
•
?
concept of normal physiological ranges.
?
3. ?
Quality assurance systems, reference materials, error analysis.
?
k.
?
Specimen collection, handling and storage, depro,teinization.
?
5. ?
Respiratory function and biochemical acid-base balance.
?
(. ?
Disorders and assessment of-acid-base equilibria.
?
7.
?
Fluid-and electrolyte regulation, osmolal'ity.
?
8
,
. ?
Renal 'anatomy, biochemistry of urine formation.
9.
Assessment of renal function.
10.
Anatomic considerations of the liver, bilirubin metabolism.
11.
Liver function tests and their role as dignostics.
1.2. ElectrophoreticasSeSsment of protein disturbances.
1.3. The immunoglobulifle: classes, structure and function..
14.
Immune mechanisms and deficiency states.
15.
Amino acids, inborn errors of metabolism.
16.
Biochemical disorders of carbohydrate metabolism.
17.
Lipids: methods of transport, interrelationship with
carbohydrate metabolism.
18'. Lipoprotein patterns in disease, cholesterol, triglycerides.
19. Pathophysiology.of the thyroid gland: laboratory
,
findings
in disease.
M. Steroid hormones, biochemical interrelationships of the.
pituitary and adrenal glands.
21.
Laboratory assessment of the pituitary-adrenal axis.
22.
fl:taostic enzymology.
?
'
?
'
?
'
?
•
25. Cardiac enzyme disturbances and their diagnostic imp1:1caton.
-2-
2k. Pancreatic secretions and malfunction in disease.
25.
Biochemistry of the gastro-intestinal system and assessment.
26.
Malabsorption.
27.
Principles of pharmacology, classes of drug action.
• ?
28. Clinical toxicology, drugs of abuse.
• ?
29. Toxicological analyses.
30.
Drug interaction in biochemical testing.
31.
Automated analyses, discrete sampling and flow systems.
32.
Laboratory data processing, and patterns of work-.flow.
33.
Field trip to clinical laboratory.
• 34.
Methodology
.
deVelOpmeflt and criteria for selection.
35.
Clinical chemistry in industrial and occupational. health.
• Library Resources Recommended for Clinical Chem 420-3
Journals and Periodicals
Appears to be adequate, although one leading Journal, i.e.
Clinica Chimica Acta, is not on the shelves. This Journal is
very costly (about $125./annum) and is being discontinued by
many libraries. The Journal is desirable but when weighed
against the cost is probably not Justifiable.
Books
The following should be acquired by the library:
1.
Tietz, N.W., Fundamentals of Clinical Chemistry, 1970
W.B. Saunders.
2.
Henry, R.J., Clinical Chemistry, Principles and Technics,
Harper and Rowe,
1964k
3.
'
Harper, H.A., Review of Physiological Chemistry, 1)4th ed.,
Lange Medical Publishers, 1973.
k. H. Varley, Practical Clinical Biochemistry, Intersôience
Books Inc., 4th ed., 1967.
Recommended Text
Baron; D.N., A Short Textbook of Chemical Pathology,?
• English Universities Press Ltd.,' 2147
p. ,
1973,
3rd
ed.
* For use as text in proposed course.
I
