S.93-21
SIMON FRASER UNIVERSITY
.
Office of the Vice-President, Academic ?
MEMORANDUM
To:
?
Senate ?
From: ?
Dr.
J
.
M. Munro
Chair, Senate Committee
on Academic Planning
Subj
ect
:
?
Restructured Biochemistry Program
Date: ?
March 17, 1993
Action undertaken by the Senate
Committee on Undergraduate Studies and the Senate
Committee
on Academic Planning (SCAP 93 - 9) gives rise to the following motion:
Motion:
?
"That Senate approve and recommend approval to the Board of Governors as
set forth in S.93 -21, the restructured Biochemistry Program including
New courses ?
BICH 221
-
3
Cellular Biology and Biochemistry
BICH 222-3 Molecular Biology and Biochemistry
BICH 321 -3
Intermediary Metabolism
BICH 322
-
3
Molecular Physiology
BICH 421 - 3 Nucleic Acids
BICH 422-3 Biomembranes
BICH 423-3 Protein Structure and Function
Deletions ?
BICH 301 -3 The Structure and Reactivity of
Biomolecules
BICH 302-3 Metabolism"
M^. "
0
SCUS93-6
. ?
SIMON FRASER UNIVERSITY
MEMORANDUM
To: R. Heath
?
From: C.H.W. Jones, Dean
Secretary to SCUS
?
Faculty of Science
Subject:
Restructured
?
Date: March 9, 1993
Biochemistry Curriculum
On March 8 1993 the Faculty of Science approved a restructured
curriculum for the undergraduate degree programme in Biochemistry as
described in the attached documentation. This restructuring represents a
fairly major revision to the programme.
The Biochemistry Programme
The Biochemistry Programme is an interdisciplinary,
undergraduate programme offered jointly by the Departments of
Chemistry and
Biosciences;
the programme is administered by the
Biochemistry Curriculum Committee of the Faculty.
In the Spring of 1992 the Biochemistry Curriculum Committee was
reconstituted to take advantage of the expertise reflected in the recently
hired new faculty members in this area. The new committee comprises:
T.B. Borgford and D. Sen (Chemistry); N.H. Haunerland and J.V. Price
(Biosciences); G. Tibbits (Kinesiology). Dr. Borgford is the Committee
Chair.
In the Summer of 1992 the Committee undertook a major review of
the Biochemistry Programme in close consultation with the Departments
of Chemistry and Biosciences. As a result of that review, a number of
significant changes were recommended which will modernize the
curriculum and which will reduce overlap between some of the present
courses. The restructured curriculum was approved by the Departments
of Chemistry and Biosciences in the Fall of 1992 and the proposal has
now received approval by the Faculty of Science Undergraduate
Curriculum Committee and the Faculty as a whole.
The Recommendation
The key features of the recommendation are summarized in the
attached memorandum from Dr. Bob Brooke, Chair of the Faculty
Undergraduate Curriculum Committee.
The Faculty of Science recommends approval of the
restructured Biochemistry Curriculum and the new courses
presented in the proposal.
The Library has provided an analysis of the proposed additional
Library holdings. The Faculty of Science will provide the funding for the
required periodicals ($2,015 p.a.) and the costs for new monographs
($3,559 p.a.). We will provide the additional funding for the less-
essential monograph holdings of $5,932 over the next two to three year
period.
Ck ?
$.
C.H.W. Jones
CHWJ :rh :Encl.
C. ?
T. Borgford, Chair
Biochemistry Curriculum Committee
R.C. Brooke, Chair
Faculty of Science Undergraduate Curriculum Committee
C
•
?
SIMON FRASER UNIVERSITY
Memorandum
TO: C.H.W. Jones, Dean ?
FROM: ?
R. C. Brooke, Chair
Faculty of Science
?
Faculty of Science
Undergraduate
Curriculum Committee
SUBJECT:
Restructured Biochemistry
?
DATE: ?
February 22, 1993
Curriculum
At a meeting on 11 February 1993, the Faculty
of
Science Curriculum
Committee unanimously approved the attached Restructured Biochemistry Curriculum
(revised 2 February 1993) which includes:
1)
recommended changes to the Major (Core) Biochemistry Program
2) ?
the introduction
of
seven new courses (proposals attached),
deletion
of
two existing courses and the phasing out
of
three courses
New Courses
BICH 221-3
Cellular Biology and Biochemistry
courses con-
222-3
Molecular Biology and Biochemistry/
taming the
321-3
Intermediary Metabolism
fundamentals of
322-3
Molecular Physiology
Biochemistry in the
J
proposed core prog.
421-3
Nucleic Acids
new U/D Bio-
422-3
Biomembranes
chemistry electives
423-3
Protein Structure and Function
?
j
?
BICH 301-3 ?
The Structure and Reactivity of Biomolecules
?
302-3 ?
Metabolism
?
The courses: ?
BISC 201-3 Cell Biology
301-3 Biochemistry - Intermediary Metabolism
401-3 Biochemistry - Regulatory Mechanism
will be phased out as the new program and new courses take effect.
r
3)
Calendar revisions to accommodate the restructured Biochemistry
Curriculum, and
4)
a proposed schedule for implementation of the courses into the new core
Biochemistry program.
Please place the Restructured Biochemistry Curriculum proposal as
summarized above on the agenda of the next Faculty of Science meeting. Thank you.
R.C. Brooke
RCB:ln:Att.
.
0
1) ?
CHEM 218 and
CHEM 255
become prerequisites for both
BICH 311
and BICH 312
Rationale: CHEM 218 (Introduction to Analytical Chemistry) and CHEM 255
(Organic Chemistry Laboratory II) teach students the basic laboratory skills necessary
in the Biochemistry lab courses BICH 311 (Analytical Biochemistry Laboratory) and
BICH 312 (Metabolism Laboratory). However, many students are choosing to take
CHEM 218 and CHEM 255 after they have already taken BICH 311 and BICH 312.
2)
CHEM 261 become a prerequisite for
BICH 403.
Rationale: Students who have not already taken CHEM
261
(Physical Chemistry)
are poorly prepared for BICH 403 (Physical Biochemistry).
3)
Biochemistry students be given the option of taking either MATH 310 or STAT 302
and,
MATH .310 will
no longer be a prerequisite for
BICH 403.
Rationale: MATH 310 (Introduction to Ordinary Differential Equations) is currently
part of the Biochemistry core to prepare students for a small number of exercises in
BICH 403 (Physical Biochemistry). Although it was not our intention to discourage
students from taking a course in differential equations, we felt that the limited
application of differential equations in BICH 403 could not justify the inclusion of
only
MATH 310 in the core. The option of taking STAT 302 (Analysis of
Experimental and Observational Data) would give students a background,
presently lacking, in experimental design and data analysis. Currently, the
prerequisite to STAT 302 is either STAT 101 or STAT 102.
Since neither of the STAT prerequisites for STAT 302 is a component of the
Biochemistry core, the Department of Mathematics and Statistics is examining
alternatives to these prerequisites. For example, it may be possible to allow MATH
151 and MATH 152 to stand as prerequisites for a new upper level statistics course
concerned with experimental design and data analysis or such a course might be
offered without prerequisites.
4)
Biochemistry students will be given the option
of
taking CMPT 101, or CMPT 102, or
CMPT 103.
Rationale: Students are currently required to take CMPT 102 (Introduction to
FORTRAN for Science Students). Although this requirement insures that
students receive training in many of the fundamentals of computing, it restricts them
to a single computer language.
The Department of Computing Science, in consultation with Curriculum Committees
from Biochemistry, Biosciences and Kinesiology, is currently examining the possiblity
of offering a more broadly based service course similar to KIN 203 (Computer
Applications in Kinesiology).
?
0
5)
Introduction of three new elective courses: 1) BICH 421-3 Nucleic Acids 2) BICH 422- 3 -
Biomembranes 3) BICH 423-3 - Protein Structure and Function.
Rationale: The three new courses will expand the number of upper division
electives available to students in the Biochemistry core program. Each course will
be offered once a year.
6)
Removal of BISC 302 from the Biochemistry Core
With the implementation of the new core program this course would be more
appropriate as an elective.
7)
Inclusion of BISC 431 -4 (3-0-6) in the Biochemistry Core
Rationale: There are relatively few laboratory courses in the current Biochemistry
Core. BISC 431 (Molecular Biotechnology) would give biochemistry students a much
needed exposure to modern laboratory techniques in molecular biology. Also,
inclusion of BISC 431 in the Biochemistry Corewould help to satisfy the
requirements for upper division credits by compensating for the removal of BISC 302.
8)
Add one credit to BICH 412 (therefore BICH 412-4 (2 - 1- 4))
Rationale: In recent years the content of BICH 412 (Enzymology) has expanded to
include an extra hour of lecture and tutorial material. The addition of one credit
hour to the vector reflects this change to the content.
9)
Integration of courses BISC 201, BISC 301, BISC 401, BICH 301 and BICH 302 (ie.
eventually these course will be removed from the calendar) and the lecture component of
BISC
405 into a suite of 4 new courses designated BICH 221 (3-1-0) (Cellular Biology and
Biochemistry), BICH 222 (3-1-0) (Molecular Biology and Biochemistry), BICH 321 (3-1-0)
Intermediary Metabolism, and BICH 322 (3-1-0) (Molecular Physiology).
Rationale: The courses slated for integration contain the fundamentals of
Biochemistry. However, the subject matter is not presently given in an integrated
or coherent manner. As a consequence, there are significant redundancies and
incongruities in the six courses. (Most notable are the courses BISC 301 and BICH
301 which have an identical syllabus, are taught from the same text book and serve
equally as prerequisites for BICH 302). By organizing the contents of the six courses
into four new offerings with specific syllabuses (please see the sample outlines
attached) redundancies and incongruities are avoided. The proposed restructuring
will make it possible to introduce molecular biology and biochemistry (in addition
to cell biology) to students in their second year. The principle benefits of this are
3
. ?
that 1) students enrolled in Biological Sciences will have exposure to subject matter
which they might not otherwise receive, and 2) instructors of third and fourth
year courses can present subject matter at a higher level.
The courses BICH 221 and BICH 222 will be offered 3 times a year and the courses
BICH 321 and BICH 322 will be offered twice a year (please see Proposal for the
Implementation of Courses below)
10) BICH 222 become a prerequisite for BISC 321
Rationale: The calendar curreently describes BISC 321 (Introduction to Molecular
Biology) as "The study of gene structure and evolution, DNA replication, and the
regulation of gene expression in bacteria and higher organisms" (please compare
with proposed calendar description and sample outline for BICH 222). The proposed
BICH 222 would serve to introduce many of these topics to students and allow the
contents of BISC 321 to be presented in greater detail and at a more advanced level.
Instructors
Instructors for the courses BICH221, B1CH222, BICH321, and B1CH322 may be drawn
from both Biological Sciences and Chemistry, and can include instructors who formerly
taught in the 5 courses removed from the calendar. For example, faculty members who are
*ualified to teach in the new program are as follows;
BICH 221 ?
Brandhorst
BICH 222
?
Brandhorst
Boone
Baillie
Borgford
Borgford
Cornell
Beckenbach
Scott
Honda
Kermode
Smith
Moore
Price
Haunerland
Sen
BICH 321 ?
Borgford
*BICH 322
?
Baillie
Cornell
Boone
Cushley
Borgford
Haunerland
Burr
Richards
Delaney
Cornell
Pinto
Price
Sen
Scott
P1-irlc
Obecause of the diversity of subject matter
in
BICH 322 this course will likely be team-taught
by two or three instructors.
51
'Proposal for the Implementation of Courses
To implement the new curriculum we have drawn up a schedule for the first offering of the
new courses (BISC and BICH core courses) and last offering of redundant courses. Current
offerings appear in italics and the new offerings are given in bold.
Semester
93-2
(BISC 201)
(BICH 302)
93-3
(BISC 201)
(BISC 301)
(BICH 301)
94-1
(BICH
221)
(BISC 301)
(BICH 301)
?
(BICH 302) ?
(BISC 401)
94-2
(BICH
221)
(BICH
222)
(BISC 301)
(BICH 302)
94-3
(BICH
221)
(BICH
222)
(BICH
321)
95-1
(BICH
221)
(BICH
222)
(BICH
321)
(BICH
322) ?
(BISC 401)
95-2
(BICH
221)
(BICH
222)
(BICH
322)
95-3
(BICH
221)
(BICH
222)
(BICH
321)
96-1
(BICH
221)
(BICH
222)
(BICH
321)
(BICH
322)
96-2
(BICH
221)
(BICH
222)
(BICH
322)
In addition, the courses BICH 421 and 422 will first be offered in 94-3 and BICH 423 will first
be offered in 95-1.
Flowcharts
On the following flow charts horizontal lines indicate corequisites and vertical lines
indicate prerequisites. Major differences from the "existing core" are indicated by bold boxes
on the flowchart of the "proposed core".
.
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*
BIOCHEMISTRY CALENDAR REVISIONS (1994/1995 Calendar): COURSES
he following revisions are necessitated by the changes to the curriculum.
(1TCt' ?
NT.y ?
rrc1
'
P e-% ? = ?
vr
Page Course Current text
Change to, add or delete
NCPF BICH
(New course:)
Cellular Biology and
(ed)
221-3
Biochemistry
A study of the molecular
processes which underlie cell
structure and function,
integrating ultrastructural,
physiological and biochemical
approaches. Modern techniques
used in the analysis of
organelle and cell function
are integral parts of the
course. (3-1-0)
?
Prerequisites:
BISC 101,
?
102 and either CHEM
103 or 150 (both CHEM 103 and
CHEN 150 are recommended as
prerequisites or
corequisites).
?
Students may
not receive credit for both
BICH 221 and BISC 201.
NCPF BICH
(New course:)
Introduction to Molecular
(ed)
222-3
Biology and Biochemistry
An introduction to DNA
replication and
recombination, RNA
transcription and protein
synthesis in the context of
their locations within the
cell and their timing in the
cell cycle. The relationship
between structure and
function of proteins and
nucleic acids will be
addressed. (3-1-0)
Prerequisite: BICH 221
?
(or
BISC 201). CHEM 250 is a
recommended prerequisite or
corequisite.
172
BICH
course removed from calendar
301-3
BICH
course removed from calendar
302-3
BICH
Prerequisite:
CHEM 155 (or
Prerequisites:
CHEM 255 (or
311-2
256). Corequisite: BICH 301.
CHEN 356), CHEM 218 and BICH
222. BICH 321 should be taken
concurrently.
BICH
Prerequisite:
CHEM 155 (or
Prerequisites:
CHEN 255 (or
______
312-2
256). Corequisite: BICH 302.
356), CHEM 218 and BICH 321.
I
U
8
BIOCHEMISTRY CALENDAR REVISIONS : COURSES
(NCPF = New course Proposal Form; ed = editorial)
Page
Course Current text
Change to, add or delete
NCPF
BICH
(New course:)
Intermediary Metabolism
(ed)
321-3
Major catabolic and anabolic
pathways and their
regulation. Particular
emphasis is placed on
bloenergetics and
experimental methods
encountered in biochemical
research. ?
(3-1-0)
Prerequisites: BICH 222 and
CHEM 250
?
(or 252). BICH 311
should be taken concurrently.
Students may not receive
credit for both 31CM 321 and
31CM 301.
NCPF
BICH
(New course:)
Molecular Physiology
(ed)
322-3
Cellular and biochemical
aspects of immunology, muscle
contraction, cell motility,
neural transmission, the
action of hormones. The
course will also explore the
cellular and molecular basis
of cancer.
?
(3-1-0)
Prerequisite: BICH 222.BICH
321 ?
(or 31CM 301) ?
is
recommended. Students may not
receive credit for both BICH
322 and BICH 302.
172
BICH
Prerequisites:
PHYS 121 (or
Prerequisites:
CHEM 261, BICH
403-3
102), MATH 310 and BICH 301.
321 (or BICH 301). BICH 413
Ordinarily, BICH 413 will be should be taken concurrently.
taken concurrently, but may
be taken subsequently to BICH
403.
31CM
... ?
(1-0-4) ?
Prerequisites: ... (2-1-4) ?
Prerequisites:
412-3
BICH 301 (or BISC 301) and
BICH 321 (or BICH 301) and
BICH 311 (or 312).
one of BICH 311 or BICH 312.
(now
412-4)
31CM
Prerequisites:
BICH 301,
Prerequisites:
BICH 321 (or
413-3
302,311 and 312. Ordinarily,
BICH 301),311 and 312. BICH
BICH 403 will be taken
403 should be taken
concurrently but may precede
concurrently.
BICH 413.
1
0
0'
?
BIOCHEMISTRY CALENDAR REVISIONS : COURSES
(NCPF = New course Pr000sal Form: ed = editorial)
I
Page
lCourse
Current text
Change to, add or delete
NCPF
BICH
(New course:)
Nucleic Acids
(ed)
421-3
Recent literature is examined
for insights into the
structure and properties of
DNA and RNA, drawing on a
variety of biochemical,
chemical and molecular
biological perspectives. ?
(3-
1-0)
?
Prerequisite:
BISC 321
NCPF BICH
(New course:)
.Biomernbranes
(ed)
422-3
A review of recent research
on the structure, dynamics,
function and biosynthesis of
membranes, membrane lipids
and proteins.
?
(3-1-0)
Prerequisites:
?
BICH 321 ?
(or
301) ?
and 322
?
(or 302) .
?
BICH
413 is recommended.
NCPF
BICH
(New course:)
Protein Structure and
(ed)
423-3
Function
The course will discuss
recent research in transition
'
state theory; specificity in
enzyme catalyzed reactions;
the use of recombinant DNA
techniques to describe and
modify enzyme catalysis; the
function of enzymes in
organic solvents; and the
development of new catalytic
activities through monoclonal
antibody techniques. ?
(3-1-0)
Prerequisites:
BISC 321, and
either BICH 321 ?
(or 301) or
322 ?
(or
?
302).
173
BISC
Prerequisite:
BISC 201
Prerequisite:
BICH
221 (or
305-3
201).
BISC
Prerequisites:
BISC 301
or
Prerequisite:
BICH 321, CHEM
313-3
BICH 302,
CHEM
252.
250 ?
(or 252).
Corequisite:
Corequisite: BISC 312.
BISC 312. Students with
Students with credit for BISC
credit for
BISC 311-3 will
311-3 will not receive credit
not receive credit for EISC
for
BISC
313-3
313-3
S
10
BIOCHEMISTRY CALENDAR REVISIONS : COURSES
(NCPF = New course ProDosal Form: ed = editorial)
?
a
Page Icourse Current text
Change to, add or delete
173
BISC
Prerequisites:
BISC 301 or
Prerequisite:
BICH 222 and
321-3
BICH 302; BISC 202.
BISC 202.
174
BISC
Prerequisites:
BISC 201,
CHEM
Prerequisites:
BICH 222,
CHEN
356-3
150 ?
(or
251) ?
and
155
?
(or
150 ?
(or
251) ?
and
155 ?
(or
256) .
256)
BISC
Prerequisites:
BISC 201,
CHEM
Prerequisites:
BICH 222,
CHEM
366-3 150 ?
(or
251) ?
and
155 ?
(or
150 ?
(or
251) ?
and
155 ?
(or
256) .
256)
BISC
Prerequisites:
BISC 301 or
Prerequisites:
BICH 322 (or
405-3
BICH 302.
BISC 305 is
302) and one of BISC 329,
recommended.
BICH 311 or ?
312.
BISC 305 is
recommended.
BISC
Prerequisite:
BISC 301 or
Prerequisites:
BICH 222,or
411-3
BICH 302,
or permission of permission of instructor.
instructors.
BISC
Prerequisite: BISC 301 or
Corequisite: BISC 321.
412-3
BICH 302; BISC 321
corequisite.
BISC
Prerequisite: BISC
321.
Prerequisite:
BISC 321
431-4
Recommended
BISC 401
and/or
Recommended
BICH 322 (or 302)
BISC 402
concurrently.
and/or
BISC 402
concurrently.
BISC
Prerequisite:
BISC 301 or
Prerequisite:
BICH 321 (or
432-3
BICH 302.
301 or 302).
175 BISC
Prerequisite:
BISC 301 or
Prerequisite:
BICH 322 (or
453-3
BICH 302,
and EISC
203
and
302),
and BISC
203
and
321.
321.
BISC
Plant Biochemistry and
Plant Molecular Biology and
457-3
Molecular Biology ...
Biotechnology
Prerequisites:
BISC 301 or
Prerequisites:
BICH 321 (or
BICH 302
and
BISC 337
or
366.
301)
and
BISC 337
or
366.
180
CHEM
Prerequisites:
BICH 301, or
Prerequisites:
BICH 321 (or
333-3
BISC 301, or CHEM 250 (or 301) or CHEM 250 (or 252) and
252) and CHEM 232.
CHEM 232.
216
KIN
Prerequisites: ?
...
BISC 201
Prerequisites: ?
...
BICH 222
305-3 ...
(or BISC 201)
KIN
Prerequisites: ?
...
BISC 201
Prerequisites: ?
...
BICH 222
306-3 .
?
..
(or BISC 201)
217
KIN
Prerequisite:
BISC 201.
Prerequisite:
BISC 222 (or
430-3
Students with credit in KIN
BISC 201).
Students with
330
may not take KIN
430
for
credit for KIN
330
may not
further credit.
It is
take KIN
430
for further
recommended that students
credit.
take BISC 301 prior to
enrolling
in KIN 430.
KIN
Prerequisites:
BISC 201,
KIN
Prerequisites:
BICH 222 (or
460-3
105
?
(formerly KIN
100), ?
142
BISC 201),
KIN
105 ?
(formerly
and 90 credit hours.
KIN
100), ?
142
and 90 credit
hours.
11
BIOCHEMISTRY CALENDAR REVISIONS: PROGRAM
(The current description of the Biochemistry Program, found on pages 147 and 148, will be replaced
with the following:)
Biochemistry Program
Associated Faculty
D.L. Baillie
Biological Sciences
A.T. Beckenbach
Biological Sciences
C. Boone
Biological Sciences
T.J. Borgford
Chemistry
B.P. Brandhorst
Biological Sciences
R.B. Cornell
Chemistry
R.J. Cushley
Chemistry
B.M. Honda
Biological Sciences
J.V. Price
Biological Sciences
W.R. Richards
Chemistry
J .
K. Scott
Chemistry
DWT
Sen
Chemistry
Smith
Biological Sciences
Advisor: ?
Dr. W.R. Richards
Rm. 6144 South Sciences Building
291-4355
Major, minor and honors programs in Biochemistry are offered by the Faculty of Science. Entry
into these programs requires the permission of the Program Advisor of the Biochemistry Curriculum
Committee.
Major Program
(120 Semester Hours)
All students taking Biochemistry must complete the core program as specified below, together
with elective courses chosen in consultation with the Biochemistry Program Advisor.
Core Program
(90-9 1 Semester Hours)
.
?
BICH 221-3
222-3
311-2
Cell Biology and Biochemistry
Molecular Biology and Biochemistry
Analytical Biochemistry Laboratory
12
312-2 Metabolism Laboratory
321-3 Intermediary Metabolism
322-3 Molecular Physiology
403-3 Physical Biochemistry
412-4 Enzymology
413-2 Physical Biochemistry Laboratory
BISC 101-4 Introduction to Biology
102-4
Introduction to Biology
202-3
Genetics
321-3
Introduction to Molecular Biology
431-4
Molecular Biotechnology
CHEM 102-3
General Chemistry I
103-3
General Chemistry II for the Physical Sciences
115-2 General Chemistry Laboratory I
118-2
General Chemistry Laboratory II
150-3
Organic Chemistry I
155-2
Organic Chemistry Laboratory I
218-3
Introduction to Analytical Chemistry
250-3
Organic Chemistry II
255-2
Organic Chemistry Laboratory II
261-3
Physical Chemistry I
333-3 Inorganic Chemistry of Biological Processes
one
?
the following courses in Computing Sciences
CMPT 101-4 Modula 2
102-3
Introduction to FORTRAN for Science Students
103-3
Introduction to PASCAL Programming
MATH 151-3
Calculus I (or 154-3 Calculus I for the Biological Sciences*)
152-3 Calculus II (or 155-3 Calculus II for the Biological Sciences*)
and either
MATH 310-3 Introduction to Ordinary Differential Equations
or
STAT 302-3 Analysis of Experimental and Observational Data
(prerequisite STAT 102).
(MATH 232-3 Elementary Linear Algebra and MATH 251-3 Calculus ifi
are recommended).
PHYS 120-3 Physics I (or 101-3 General Physics 1*)
121-3 Physics II (or 102-3 General Physics 11*)
.
13
Course alternatives marked with an asterisk are possible only for students who have
Oransferred to Biochemistry from another program. Students who have declared (or intend to declare)
a biochemistry major or honors program should
not
register for these alternative courses.
In addition to the core program, students majoring in Biochemistry must complete 30 semester
hours of electives, at least 12 of which must be upper division credits (excluding EDUC 401 to 407).
Nine semester hours must be taken in subjects outside the Faculty of Science, including a minimum of
6 hours from the Faculty of Arts. Further BSc general degree regulations are given in the
Faculty of
Science
section.
Although many variations are possible, a student entering with BC High School Chemistry 12,
Algebra 12 and Physics 12 (or equivalents) might take the following typical program.
LEVELS 1 and 2:
BISC 101-4 and 102-4
CHEM 102-3,115-2,150-3 and 155-2,
MATH 151-3 and 152-3,
PHYS 120-3 and 121-3
Total 30 semester hours
LEVELS 3 and 4:
BICH 221-3 and 222-3
BISC 202-3
CHEM 103-3,118-2,218-3,250-3 and 255-2
CMPT 101-4 or 102-3 or 103-3
6 hours of electives
Total 31 -32 semester hours
LEVELS 5 and 6:
BICH 311-2,312-2,321-3 and 322-3
BISC 321-3
CHEM 261-3
MATH 310-3 or STAT 302-3,
9 hours of electives
Total 28 semester hours
LEVELS 7 and 8:
BICH 403-3,412-4 and 413-2
BISC 431-4
CHEM 333-3
15 hours of electives
Total 31 semester hours
Students entering without the equivalent of B.C. High School Chemistry 12 may not enter
CHEM 102-3, but may begin with CHEM 101-3 and 106-2 and then follow a program similar to the
One above.
14
Honours
(132-133 semester
Program
hours)
?
.
In addition to the core courses shown for the major program, students taking honors in
Biochemistry must complete a further 42 semester hours, to include: CHEM 357-3 (Chemical and
Instrumental Methods of Identification of Organic Compounds), and either BICH 491-5
(Undergraduate Research) or BICH 493-15 (Individual Study Semester), plus at least 9 semester hours
of credit from the following list of courses:
BICH 421-3 Nucleic Acids
BICH 422-3 Biomembranes
BICH 423-3 Protein Structure and Function
BISC 402-3
Molecular Genetics
BISC 453-3
Advanced Developmental Biology
BISC 457-3
Plant Biochemistry and Molecular Biology
CHEM 450-3 Mechanistic Organic Chemistry
CHEM 411-3 Crystal Structure Analysis
or with the permission of the Undergraduate Advisor
BICH 420-3 Selected Topics in Contemporary
.
Biochemistry
BICH 490-3 Directed Study in Advanced Topics of Biochemistry
BISC 471-3 Special Topics in Biology
BISC 472-3 Special Topics in Biology
BISC 473-3 Special Topics in Biology
plus 9 semester hours in courses outside the Faculty of Science (including 6 hours in the
Faculty of Arts, but excluding EDUC 401 to 407); and sufficient upper division courses to bring the
total number of upper division credit to at least 60 semester hours. Further BSc. honors requirements
are given in the
Faculty of
Science
section.
Minor Program
(64-66 semester hours minimum)
Lower Division Requirements
(50 semester hours minimum)
BICH 221-3 and 222-3
BISC 101-4 and 102-4
Cl-rEM 102-3, 103-3, 115-2, 118-2, 150-3, 155-2, 218-3, 250-3 and 255-3
MATH 151-3 and 152-3 (or 154-3 and 155-3)
PHYS 120-3 and 121-3 (or 101-3 and 102-3)
Upper Division Courses
(15-17 semester hours)
BICH 311-2,312-2,321-3,322-3
and at least two of
BICH 403-3 (requires CHEM 261), 412-4, 413-2, 420-3, 421-3, 422-3, 423-3, 490-3
15
0 ?
BISC 321-3 (requires BISC 202)
Co-operative Education Program
Major and honours students in Biochemistry may apply for admission into the Science Co-
operative Education Program. The program includes four work semesters during the normal
academic program. For further details, refer to the
Co-op Education
section.
S
S
16
SENATE COMMITTEE ON UNDERGRADUATE STUDIES
?
NEW COURSE PROPOSAL FORM
rT
T1 ?
I
I
1 TI) ?
iJ
Abbreviation Code:_BICH Course Number _221 Credit Hours:_3_Vectoc _3-1-0
Title of C
Calendar Description of Course:
A study of the molecular processes which undeie cell structure and function, integrating
ultrastructural, physiological and biochemical approaches. Modern techniques used in the
analysis of organelle and cell function are integral parts of the course.
Nature of Course:Lecture
Prerequisites (or special instructions):
BISC 101, BISC 102, and either CHEM 103 or CHEM 150 (both CHEM 103 and CHEM 150 are
recommended as prerequisites or corequisttes). Students may not receive credit for both BICH
221 and BISC 201.
What course (courses), if any, is being dropped from the calendar if this course is approved?
2.
Scheduling
How frequently will the course be offered? three times per year
Semester in which the course will first be offered? ?
94-1
Which of your present faculty would be available to make the proposed offering possible?
M. Moore, A. Kermode, C. Boone, J. Scott
3.
Objectives
of
the Course
The companion courses BICH 221,222,321 and 322 integrate the instruction of cell and
molecular biology, biochemistry and molecular aspects of physiology.
To provide an integrated overview of cell function.
4.
Budg
etary and Space Requirements (for information only)
What additional resources
will
be required in the following areas?
Faculty: ?
none
Staff: ?
none
Library: ?
none
Audio Visual: none
Space: ?
none
Equipment ?
none
5.
Approval
I
=
Ff.
lit
I
LI 116 ?
C
Deiwtment Chair
?
Dean
S
?
BICH 221
Cellular Biology and Biochemistry
Sample outline:
week 1: Overview of the cell and its chemical components
week 2 Introduction to catalysis and energy metabolism
week 3: The cytosolic compartment: glycoysis and lipid breakdown
week 4: The mitochondrion: structure and function (citric acid cycle, oxidative phosphorylation)
week 5: The chloroplast: structure and function (photosynthesis, Calvin cycle)
week 6: Membranes: structure and functions
week 7: Membrane transport: Ion pumps and channels
week 8: The endomembrarie system: ER, Golgi and intracellular sorting
week 9: Lysosomes and peroxisomes
week 10: The cytoskeleton, cell movement
week 11: Cell signalling: strategies, cell junctions, plasmodesmata
week 12: Cell signalling: receptors and second messengers
week 13: Extracellular matrix, cell-cell recognition and adhesion
Recommended textbooks:
Alberts, Molecular Biology of the Cell
Stryer, Biochemistry
0
SENATE COMMITFEE ON UNDERGRADUATE STUDIES
?
NEW COURSE PROPOSAL FORM
LW!1 r ?
2
rnri-i-ii r,
Abbreviation code:
— BCE — course Number--222--Credit Hours:—I--Vector
3-1-0
Calendar Description of Course:
An introduction to DNA replication and recombinotion. RNA transcription and protein synthesis
in the context of their locations within the cell and their timing in the cell cycle. The relationship
between structure and function of proteins and nucleic acids will be addressed.
Nature of Course:Lecture
Prerequisites (or special instructions):
BICH
221
(or
BISC 201). CHEM 250
is a recommended prerequisite or corequisite.
What course (courses), if any, is being dropped from the calendar if this course is approved? N/A
2.
Scheduling
How frequently will
the course be offered?
?
three times per year
Semester in which the course
will
first be offered?
?
94-2
Which of your present faculty would be available to make the proposed offering possible?
T. Borgford, B. Honda, D. Sen,
M.
Smith
3.
Objectives of the Course
The companion courses BICH 221.222.321 and 322 integrate the instruction of cell and
molecular biology, biochemistry and molecular aspects of physiology.
To provide on integrated overview of molecular and biochemical processes.
4.
Budgetary and Space Requirements
(for information only)
What additional resources
will be required in the following areas?
Faculty: ?
none
Staff: ?
none
Library: ?
none
Audio Visual: none
Space: ?
none
Equipment: ?
none
5.
Approval
Date1
.I
1 t't,
?
CA (c)C)
Department Chair
?
Dean
SCUS 73-74b: (When
competing this form, for instructions see Memorandum SCUS
73-74a.) ?
f (
S
BICH 222 ?
Introduction to Molecular Biology and Biochemistry
Sample outline:
week 1:
?
Chemical Equilibria, free energy, catalysis
week 2:
?
Proteins I: amino acids, polypeptides, folding
week 3:
?
Proteins II: enzyme classes, serine protease, haemoglobin
week 4:
?
DNA Structure
week 5: ?
DNA replication; repair and mutagenesis
week 6: ?
Prokaryotes
vs.
Eukaryotes; The Nucleus; Chromosome structure; Chromatin
week 7: ?
The Cell Cycle; Chromosome Replication; Mitosis and Meiosis
week 8:
?
Recombination; Plasmids and Viruses
week 9: ?
Recombinant DNA and Techniques
week 10:
?
The Flow of Genetic Information; Prokaryotic Transcription; the lac operon
week 11:
?
Eukaryotic transcription; poly A and capping; Splicing
week 12:
?
Protein Synthesis
week 13: ?
Protein Degradation; Urea Cycle; Makeup Class
Recommended textbooks:
Alberts, Molecular Biology of the Cell
Is
Stryer, Biochemistry
o.
SENATE COMM1TrEE ON UNDERGRADUATE STUDIES
?
NEW COURSE PROPOSAL FORM
1. Calendar Information
Abbreviation Code:
-
DIM
-
Course Number. 321 Credit Hours:3 Vector _3-1-0
Title of Course: ?
Intermediary Metabolism
Calendar Description of Course:
Major catabolic and anabolic pathways and their regulation. Particular emphasis is placed on
bioenergetics and experimental methods encountered in biochemical research.
Nature of Course:Lecture
Prerequisites (or special instructions):
BICH 222 and CHEM 250 (or 252). BICH 311 should be taken concurrently. Students may not
receive credit for both BICH 321 and BICH 301.
What course (courses), if any, is being dropped from the calendar if this course is approved?
BICH 301, BICH 302.
2.
Scheduling
How frequently will the course be offered? twice per year
Semester in which the course will first be offered? ?
94-3
Which of your present faculty would be available to make the proposed offering possible?
P. Cornell, R. Cushley, N. Haunerland, W. Richards
3.
Objectives of the Course
The companion courses BICH 221,222.321 and 322 integrate the instruction of cell and
molecular biology, biochemistry and molecular aspects of physiology.
To teach metabolism and mechanistic aspects of biochemical reactions at an advanced level.
4.
Budgetar
y
and Space Requirements (for information only)
What additional resources will be required in the following areas?
Faculty: ?
none
Staff: ?
none
Library:
?
none
Audio Visual: none
Space:
?
none
Equipment: ?
none
5.
Date_________________
Approval
F ?
IS,
?
01
?
.,1
11,
.
.
BICH 321
?
Intermediary Metabolism
A comprehensive treaty of intermediary metabolism. The course covers major catabolic and
anabolic pathways and their regulation. Particular emphasis is placed on bioenergetics and
experimental methodology encountered in biochemical research.
Sample outline:
week 1: Design of metabolic pathways, structure and function of coenzymes
week 2 Structure and catabolism of carbohydrates; carbohydrate analysis
week 3: Structure and catabolism of lipids; lipid analysis
week 4: Structure and catabolism of amino acids; peptide and amino acid analysis
week 5: Bioenergetics: citric acid cycle
week 6: Bioenergetics: mitochondrial electron transport
week 7: Bioenergetics: photosynthesis
week 8: Bioenergetics: photosynthesis
week 9: Biosynthesis of carbohydrates; complex carbohydrates
week 10: Biosynthesis of lipids; chemical synthesis of lipids
week 11: Biosynthesis of amino acids; peptide synthesis
week 12: Biosynthesis of nucleotides and coenzymes; chemical synthesis of DNA
week 13: Intergration of metabolisms; metabolic diseases
Recommended textbooks:
Stryer, Biochemistry
Zubay, Biochemistry, 3rd edition, 1993
2.-2-.
SENATE COMMITTEE ON UNDERGRADUATE STUDIES
NEW COURSE PROPOSAL FORM
1.
Calendar
Information ?
Department ?
Biosciences/Chemistry
Abbreviation Code:
BICH_
Course Number 322 ?
_Credit hours: _ Vectoc _3-1-0
Title of Course:
Molecular Ph4iology
Calendar Description of Course:
Cellular and biochemical aspects of immunology, muscle contraction, cell motility, neural
transmission, the action of hormones. The course will also explore the cellular and molecular
bases of cancer.
Nature of Course:
Lecture
Prerequisites (or special instructions):
BICH 222. BICH 321 (or BICH 301) is recommended. Students may not receive credit for both
BICH 322 and BICH 302.
What course (courses), if any, is being dropped from the calendar if this course is approved?
2.
Scheduling
How frequently will the course be offered?
twice per year
Which
Semester
of your
in which
present
the
faculty
course will
would
first
be
be
available
offered?to
?
make the
95-1proposed ?
offering possible?
0
T. Borgford, J. Burr, J. Scott, D. Sen, W. Richards
3.
Objectives of the Course
The companion courses BICH 221,222,321 and 322 integrate the instruction of cell and
molecular biology, biochemistry and molecular aspects of physiology.
To teach selected topics in molecular physiology at an advanced level.
4.
Budgetary _and _Space _Requirements (for information only)
What additional resources will be required in the following areas?
Faculty: ?
none
Staff: ?
none
Library: ?
The following journals are requested: Bioessays and Current Opinion in Cell Biology.
Audio Visual: none
Space: ?
none
Equipment
5. Apgroval?
none
?
•
?
Date _I
S ?
cy ___\ .
?
Department Chair
?
Dean
SCUS 73-74b: (When competing this form, for instructions see Memorandum SCUS 73-74a.)
Molecular Physiology
?
BICH
322
Sample Outline
week 1: ?
Immunology: Antibodies and Humoral Immunity
week 2:
?
Immunology: Cell mediated Immunity I
week 3: ?
Immunology: Cell mediated Immunity II; The Complement system.
week 4:
?
The Nervous System: Cells and Excitable membranes
week 5: ?
The Nervous System: Synaptic Transmission
week 6:
?
Muscle Contraction
week 7:
week 8:
week 9:
week 10:
week 11:
week 12:
week 13:
Cell Motility
Membrane Transport
Hormones and strategies of Chemical Signalling
Signal Transduction: Mechanisms I
Signal Transduction: Mechanisms
II
Cancer: Cellular Aspects
Cancer: Molecular Genetic Aspects
Texts*: Molecular Biology of the Cell by B. Alberts et al.
Biochemistry by L. Stryer
* It is expected that these textbooks will be supplemented in specific cases with material from
more advanced texts and from review papers.
24.
SENATE COMMITTEE ON UNDERGRADUATE STUDIES
?
NEW COURSE PROPOSAL FORM
1. Calendar Information
Abbreviation Code: _BICH Course Number:421 Credit Hours:_3
?
Vector: 3-1-0
Title of Course: Nucleic Acids
Calendar Description of Course:
Recent literature is examined for insights into the structure and properties of DNA and RNA,
drawing on a variety of biochemical, chemical and molecular biological perspectives.
Nature of Course:Lecture
Prerequisites (or special instructions):
BISC 321
What course (courses), if any, is being dropped from the calendar if this course is approved? N/A
2.
Scheduling
How frequently will the course be offered?
?
once per year
Semester in which the course will first be offered?
?
94-3
?
S
Which of your present faculty would be available to make the proposed offering possible?
D.Sen
3.
Objectives
of
the
Course
To study nucleic acid structure and properties at an advanced level.
4.
Budgetary and Space
Requirements
(for information only)
What additional resources will be required in the following areas?
Faculty:
?
none
Staff:
?
none
Library: ?
The following journals are requested: Current Opinion in Structural Biology and Current
Opinion in Genetics and Development.
Audio Visual: none
Space:
?
none
Equipment ?
none
5.
Date
Approval
(-d
C
/
Department Chair
?
Dean
SCUS 73-74b: (When competing this form, for instructions see Memorandum SCUS 73-74a.)
5.
Date
APProvaIF
- -. -,
Is
ii
g%e
Department Chair
?
Dean ?
Chair SCUS
SCUS 73-74b: (When competing
this
form, for instructions see Memorandum SCUS
73-74a.)
00
SENATE COMM1TFEE ON UNDERGRADUATE STUDIES
?
NEW COURSE PROPOSAL FORM
P-J
?
1. Calendar
Information
Abbreviation Code: _
BICH ?
Course Number _422 ?
Credit hours: _3
?
Vector.
3-1-0
Title of Course:
Biomembranes
Calendar Description of Course:
A review of recent research on the structure, dynamics, function and biosynthesis of
membranes, membrane lipids and proteins.
Nature of Course:
Lecture
Prerequisites (or special instructions):
BICH 301 /BICH 302 until replacement by BICH 321 /BICH 322
BICH 321 (or 301) and 322 (or 302). BICH 413 is recommended.
What course (courses), if any, is being dropped from the calendar if this course is approved? N/A
2.
Scheduling
How frequently will the course be offered? ?
once per year
Semester in which the course will first be offered? ?
94-3
Which of your present faculty would be available to make the proposed offering possible?
R. Cornell
3.
Objectives of the Course
To give students an understanding of biological membranes and to familiarize students with
current major research initiatives in the field
4.
Bud g etary _and _Space _Requirements (for information only)
What additional resources will be required in the following areas?
Faculty: ?
none
Staff: ?
none
Library: ?
none
Audio Visual: none
Space: ?
none
Equipment: ?
none
S
SENATE COMMITTEE ON UNDERGRADUATE STUDIES
?
NEW COURSE PROPOSAL FORM
1.
Calendar
Information ?
Department: _Biosciences/Chemistry
Abbreviation Code:_BICH Course Number-421-Credit, Hours:_3 Vector 3-1-0
Title
Calendar Description of Course:
Recent research in transition state theory; specificity in enzyme catalyzed reactions, the use
of
recombinant DNA techniques to describe and modify enzyme catalysis, the function of
enzymes in organic solvents, and the development of new catalytic activities through
monoclonal antibody techniques.
Nature of Course:Lecture
Prerequisites (or special instructions):
BISC
321
and either BICH
321
(or BICH
301)
or BICH
322
(or BICH
302).
What course (courses), if any, is being dropped from the calendar if this course is approved? N/A
2.
Scheduling
How frequently will the course be offered?
?
once oer year
Semester in which the course will first be offered? _95-1
Which of your present
faculty
would be available to make the proposed offering possible?
T. Borgford
3.
Objectives
of the Course
To study protein and enzyme structures, functions and catalysis at an advanced level.
4.
Budgetary and Space Requirements (for information only)
What additional resources will be required in the following areas?
Faculty: ?
none
Staff: ?
none
Library:
?
The following journal is requested: Current Opinion in Structural Biology.
Audio Visual: none
Space:
?
none
Equipment:
?
none
5.
Date__________________
Approval ?
g I'i1,3
?
O ?
,rr.9- c -
?
2 ?
3'
Department Chair
?
Dean
SCUS 73-74b: (When competing
this form, for
instructions see Memorandum SCUS 73-74a.)
..
?
SIMON FRASER UNIVERSITY
BIOCHEMISTRY CURRICULUM COMMITTEE
MEMORANDUM
To: ?
Dr. R. Heath
From: ?
Dr. T. Borgford, Chair of the Biochemistry Curriculum Committee
Subject: ?
Grading Schemes for New Biochemistry Courses
Date: ?
February 17, 1993
The purpose of this memorandum is to explain the grading schemes for students in each
of the seven new Biochemistry courses proposed in SCUS 93-6.
•
1) Students in the lower division courses BICH 221, 222, 321 and 322 will be evaluated by two
midterm examinations, each comprising 25% of the final grade, and an end of term examination
comprising 50% of the final grade.
2) Students in the upper division courses BICH 421, 422 and 423 will be evaluated on the basis of
a combination of oral presentations and term papers worth 50% of the final grade, plus an
examination worth 50% of the final grade.
Dr. Thor Borgford
0
^s
SIMON FRASER UNIVERSITY
?
.
WA. C. BEWNE77 LIBRARY ?
MEMORANDUM
To:
?
Dr. T. Borgford
?
From: Ralph Stanton
Collections Librarian
Subject:
Library Requirements for
Biochemistry Curriculum
?
Date: March 4, 1993
I have read the documentation you supplied me with regarding the seven new course offerings
(BICH 221, 222, 321, 322, 421, 422, 423) in Biochemistry. We recognize that the historical
inadequacies of our collection cannot be corrected on the backs of single courses and that it is
often difficult to assign specific collection gaps to particular courses. Nevertheless, we believe
it is important to take the opportunity provided by these assessments to analyze and evaluate
the existing collections as carefully and completely as possible within the time constraints
allowed. Our dual
-
intention is to inform the community about the relative strengths and
weaknesses of the collection and to define appropriate support for these particular courses.
In assessing our library holdings in each case I compared holdings of the three University
libraries in B.C.for major subject headings associated with the course. The findings for this
part of the process is given under each course number and more details are included in the
attached worksheets. In virtually all subjects our holdings are substantially superior to the
University of Victoria's but generally inferior to UBC's.
Using Library of Congress subject classification numbers derived from the subject headings
list I compared our holdings to our peer group on the OCLC/AMIGOS CD-ROM system. We
compared only for materials held by at least 20% of the libraries in our peer group and only for
items published in the last five years of AMIGOS' holdings.
In other words our analysis is
based on a very conservative sampling of the possible universe of titles in these LC numbers.
Since the topics of the courses are interrelated and there is some overlap in LC numbers
between courses I report these findings at the end of the course sequence.
3111
.
. Page 2
Dr. T. Borgford
March 4, 1993
All courses are for three credit hours. Periodical indexes are adequate for all courses. Here
are our
findings:
BICH 221 Cellular Biology and Biochemistry
This course replaces BICH 201 Cell Biology. It will be offered 3 times a year and the
enrollment is about 200 students per semester. Our holdings are substantially inferior to those
of UBC in five of the seven subject headings. The greatest gaps are for
Cells,
UBC has 159
titles and we have 48,
Energy Metabolism
121 to 46, and
Cell Differentiation
84 to 56.
We think that the data shows that the monograph collection is not adequate in this area.
However, the serials collection appears to be adequate for this
course.
BICH 222 Introduction to Molecular Biology and Biochemistry
This is described as an "original" course, it will be offered three times a year to about 200
students per semester. Of the seven subject headings identified we are substantially inferior to -
UBC in four. The greatest gaps are in
Proteins
219 to 113, and
Amino Acids 61
to 26.
We think that the data shows that the monograph collection is not adequate in this area.
However, the serials collection appears to be adequate for this
course.
1CH 321 Intermediary Metabolism
This course replaces BICH 301 The Structure and Reactivity of Biomolecules. It will be offered
twice a year to 75 - 100 students per offering. Of the seven subject headings identified we are
substantially inferior to UBC in two;
Biochemistry
828 to 321 (the difference is less than
apparent because we use Biological Chemistry where we have 331 titles) and
Metabolism
226
to 62.
We think that the data shows that the monograph collection is not adequate in this area.
However, the serials collection appears to be adequate for this course.
0
Page 3
Dr. T. Borgford
March
4,
1993
BICH 322
Molecular
Physiology
This course
r
'replaces BICH 302 Genetic Analysis. It will be offered twice a year to between 75
and 100 students per offering. Of the seven subject headings identified our holdings were
inferior in all seven. The greatest gaps were in
Immunology
247 to 74,
Hormones
140 to 55,
Nervous
System
251 to 76 and
Cancer Cells
63 to 20.
The course proposal form suggests the journals
Bloessays
($ 362.18 )
and
Current Opinion in
Cell Biology ($527.22) as necessary for this course.
We think that the data shows that the monograph collection is not adequate in this area. With
the two added titles, the serials collection will be adequate for this course.
NOTE: the
three following courses have previously been taught as special topics courses
under
the
420 number. Special topics courses,
to
date, have normally been created without
reference
to
the need for Library resources.
BICH
421
Nucleic Acids
This course will be offered once per year to between 20 and 30 students. Our holdings are
inferior to UBC's in three of the four subject headings.
The course proposal form requests the journal
Current Opinion in Genetics and
Development
($527.22) as necessary for this course.
We think that the data shows that the monograph collection is not adequate in this area. With
the added title, the serials collection will be adequate for this course.
fiLCH 422
Biomembranes
This course will be offered once per year to between 20 and 30 students. For the subject
heading Membranes - Biology our holdings are close to UBC's, in the subject heading Lipids
they have 90 we have 2. We think that the data shows that the monograph collection is not
adequate in this area. Serials are adequate for this course.
?
is
^k
A
Page 4
W Dr. T. Borgford
March 4, 1993
BICH 423 Protein Structure and Function
This coursewill be offered once per year to between 20 and 30 students. Our holdings are
inferior to UBC in the four subject headings identified;
Enzymes
270 to 133,
antibodies,
monoclonal
37 to 8,
Proteins
231 to 113 and Recombinant DNA 42 to 25.
The course. proposal form requests the journal
Current Opinion in Structural Biology
($598.69)
as a necessary addition.
We think that the data shows that the monograph collection is not adequate in this area. With
the addition of one title, the serials collection should be adequate for this course.
.
SUMMARY OF AMIGOS FINDINGS.
In this summary we have not included an estimate of the number of existing library materials
which should be duplicated due to the high use evidenced during title, searches or this survey
and the large enrolments in these courses.
Given the large number of students enrolled in these courses we think our estimates are
modest. We should also note that the Library budget line for Biological Sciences has
increased substantially in recent years due mainly to the rising cost of scientific serials. A
serials review has recently been conducted for this Department so the current complement of
serials is appropriate.
Our interrogation of the AMIGOS system confirms the impression gained from the comparison
with UBC. Our holdings show a consistent deficit.
We investigated 30 Library of Congress call numbers or call number ranges using the latest
five year holdings for titles owned by 20% or more of a'peer group
of
45 large academic
libraries with holdings less than 1,000,000 monographs. This choice
of
peer group is
consistent with the conservative approach we have taken with this analysis; our real peer
group is the one above i.e. greater than 1,000,000 monographs. We found a total
of
487
Page
Dr. T. Borgford
?
.
March 4, 1993
items. Of these SFU lacks 179. Of these 27 were thought to be irrelevant so the total missing
is 152.
The per volume cost (based on actual costs during the 1991-1992
.
year) of titles in this field is
$118.65. We would like to purchase a percentage of the missing 152 items, say 50 at a one
time cost of $5,932.50.
We also need to pick up some of the material we are not now collecting. We estimate this
number to be 30 per year (derived by dividing the 152 number by 5 (years)).. The recurring
cost is $3,559.50. We hope the additional books purchased will be useful for other courses in
the Department.
SUMMARY OF COSTS
One Time Costs:
Monographs
?
$5,932.50
Cost per course
?
847.50
Cost per student
?
3.51
Recurring Costs, Per Year:
Monographs ?
$3,559.50
Serials ?
2,015.31
Total ?
$5,574.81
Cost per course
?
$796.40
Cost per student
?
$
3.30
^5-
Page 6
W Dr.
T.
Borgford
March 4,
1993
RECOMMENDATION
We
believd the
recurring costs are essential for the adequate support of these courses. Both
the Department
and
the
Library
have stated that
four journals are required. This would cost
$2,015.31 per
year
including binding costs ($287.90 per course or $1.19 per student).
We believe it is essential to increase monograph purchases in this area by about 30 volumes.
per year in order to avoid the inevitable compounding
of past problems in future years. This
would cost $3,559.50 ($508.50 per course or $2.11 per student).
In addition it would be highly desirable, although perhaps not essential for these particular
courses, to fill 50 of the significant gaps in the monograph collection at an additional, one time,
cost of $5,932.50 ($847.50 per course or $3.51 per student).
0
Attachment 1,3 pages
^L
RS/eg
c.c. Sharon Thomas
?
Ted Dobb
0
is
COURSE ASSESSMENT WORKSHEET
?
COURSE No.: BICH 221
L.C. SUBJECT HOLDINGS
UVIC
SFU
UBC
CatalysisCells
1318
4887
159
111
ChioroplastsMembranes
Energy Metabolism(Biology)
39
102
4682
17
121
21
91
Cell Interaction
ii
32
38
Cell Differentiation
16
56
84
TOTAL
109
368
625
COURSE ASSESSMENT WORKSHEET
?
COURSE No.: BICH 222
L.C. SUBJECT HOLDINGS
UVIC
SFU
UBC
Chemical Equilibrium
8
40
38
Proteins
27
113
S ?
219
Amino Acids
9
26
61
Polypeptides
0
4
3
Chromosomes
14
52
72
Eukaryotic Cells
10
22
22
Protein Biosyntheses
0
19
32
TOTAL
68
276
447
/
COURSE ASSESSMENT WORKSHEET
?
COURSE No.: BICH 321
L.C. SUBJECT HOLDINGS
UVIC
SFU
UBC
Biological Chemistry
3
331
17
Bioenergetics
31
71
86
Biochemistry
87
20
828
Metabolism
16
62
226
Physiological Chemistry
i
28
16
Carbohydrate Metabolism
o
5
13
Photosynthesis
23
64
85
TOTAL
161
581
1271
COURSE ASSESSMENT WORKSHEET
COURSE No.:
BICH 322
L.C. SUBJECT HOLDINGS
UVIC
SFU
UBC
Immunology
32
74
247
Muscle Contraction
8
28
47
Hormones
14
55
140
Nervous System
24
76
251
Cancer Cells
5
20
63
Cancer - Somatic Aspects
6
2
32
Cancer - Molecular Aspects
o
1
7
TOTAL
89
256
787
0
COURSE ASSESSMENT WORKSHEET
COURSE No.:
BICH 421
L.C. SUBJECT HOLDINGS
UVIC
SFU
UBC
Nucleic
CatalysisGenetic-TranscriptionGenetic
AcidsRegulation
?
.
23
19193
258757
7
111
38
93
27
TOTAL
64
176
269
COURSE ASSESSMENT WORKSHEET
COURSE No.: BICH 422
L.C. SUBJECT HOLDINGS
?
UVIC ?
SFU ?
UBC
LipidsMembranes ?
- Biology
?
39
13
??
82
2 ??
90-
91
TOTAL ?
52 ?
84
COURSE ASSESSMENT WORKSHEET
COURSE No.:. BICH 423
L.C. SUBJECT HOLDINGS
?
UVIC ?
SFU ?
UBC
Enzymes ?
49 ?
133 ?
270
Antibodies
Recombinant
Proteins ?
- MonoclonalDNA
??
27
177
???
11325
8
???
213
42
37
TOTAL ?
100 ?
279 ?
562
?
Is
3
1
1 1
