ia

?

S.99-56

0

?

SIMON FRASER UNIVERSITY

OFFICE OF THE VICE-PRESIDENT, ACADEMIC ?

MEMORANDUM

To: ?

Senate

From: ?

J. M. Munro, Chair

Senate Committee on Academic Planning

Subject: ?

Faculty of Science -

Establishment of the Department Molecular Biology

and Biochemistry

(SCAP Reference: SCAP 99-27)

Date: ?

September 14, 1999

Action undertaken by the Senate Committee on Academic Planning gives rise to

the following motion:

0 ?

Motion:

"that Senate approve and recommend approval to the Board

of Governors as set forth in S.99 -

56,

the establishment of the

Department of Molecular Biology and Biochemistry effective April

1,2000-

io

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SCAP 99-27

SIMON FRASER UNIVERSITY

MEMORANDUM

To: ?

Alison Watt, Secretary

SCAP

From: C.H.W. Jones, Dean,

Faculty of Science

.

Subject: Formation of a New Department -

?

Date: August 11, 1999

Molecular Biology and Biochemistry

At its meeting of March 23, the Faculty of Science approved the proposal for the

formation of a Department of Molecular Biology and Biochemistry as outlined in the

attached paper.

Please include this item on the agenda of the next meeting of SOAP for

consideration and approval.

-

C.H.W. Jones

Enclosure

C. ?

A.T. Beckenbach

0

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Proposal

for the formation

of a new Department

Department of Molecular Biology and Biochemistry

We propose to consolidate the Undergraduate Program in Biochemistry with the

Graduate Program in Molecular Biology and Biochemistry, to create a single

administrative unit, the Department of Molecular Biology and Biochemistry.

We provide a brief history of the Biochemistry Program at Simon Fraser

University, and of the Institute of Molecular Biology and Biochemistry (IMBB), as well as

an overview of the current status of the undergraduate and graduate programs. An

assessment of the potential budgetary implications and benefits of the proposed

administrative changes is also included.

It should be emphasized that no new programs are proposed. Our proposal is

for an administrative reorganization that will lead to increased efficiency in the operation

of these programs and will result in clearer distinctions between our new Department

and the Departments

of

Chemistry and Biological Sciences. No new faculty or

administrative expenditure will be required to implement this proposal.

Brief History of the Biochemistry Program and the IMBB

The biochemistry program at SFU and establishment of the IMBB

The Biochemistry B.Sc. program was established as an interdepartmental

initiative involving faculty from Chemistry and Biological Sciences. In 1984 an external

review committee assessed the program and concluded that it had many gaps. The

committee recommended that the program be upgraded to provide a contemporary

educational experience for its undergraduate and graduate students—one which would

provide an appropriate breadth and depth of quality course work in cellular and

molecular biology, as well as biochemistry. It proposed the formation of an Institute

of

Molecular Biology and Biochemistry to foster research and graduate training, and to

provide a sufficient number

of

faculty and breadth

of

expertise for the Biochemistry

program. The committee identified a core

of six

faculty members in Chemistry and

Biosciences having appropriate expertise and research interests to be founding

members

of

the IMBB and recommended that a comparable number

of

new faculty be

hired by the IMBB. While not explicitly stated in its report, the committee anticipated

that the IMBB would evolve into a

fully

independent department after the new faculty

had arrived and the revamped B.Sc. and graduate programs had been implemented.

This proposal thus represents the culmination

of

a process that began 15 years ago.

The IMBB was formally established in 1987 with the six charter members. Using

an allocation

of

base budget funds from the Funds for Excellence in Education

program, the IMBB initiated a faculty recruitment program which hired six new faculty,

p

---

including a Director. With the departure of one founding member, and addition of three

new members from SFU departments, the IMBB now has

14

members. In addition, the

IMBB has 13 associate and one affiliate members. As it was not feasible for the

existing departments to provide laboratory and office space for a group of this size, a

proposal for construction of a new building was submitted and approved. The South

Sciences Building (SSB)was completed in 1993. The 14 full members of the IMBB

now occupy contiguous laboratory and office space in the new building. The IMBB has

an administrative office in the SSB, separate from the administrative offices of the

Departments of Chemistry and Biological Sciences. It provides all of the clerical

services required for its members and their graduate students, post-docs and research

associates (approximately 100 people) and for the undergraduate biochemistry program

and the graduate degree programs in molecular biology and biochemistry.

The MBB Graduate program

In 1994, the IMBB proposed the establishment of M.Sc. and Ph.D. programs in

molecular biology and biochemistry, including a set of MBB graduate courses and

degree requirements. The program was initiated in 1995 as separate programs in the

Departments of Chemistry and Biological Sciences. Administrative authority was

transferred to the IMBB in September of 1998, unifying the two programs into a single

MBB Graduate Program. This step eliminated the unnecessary duplication of effort that

had resulted from dividing the program between the two departments and the IMBB. A

•

?

majority of the students enrolled in the separate programs transferred to the new unified

MBB Graduate Program. Our program now includes 32 students, 16 enrolled in the

M.Sc. and 16 in the Ph.D. programs. An MBB Graduate Program Committee, selected

by members of the IMBB, oversees the program and reports to the Director of the

IMBB. The Director reports to the Dean of Graduate Studies on matters pertaining to

the graduate program. The MBB Graduate Program is described in Appendix 1.

The Biochemistiy B.Sc. Program

For many years, the responsibility for financial and academic administration of

the Biochemistry undergraduate degree program resided with the Department of

Chemistry. In 1995, that authority was transferred to the IMBB, and in 1996 budgetary

responsibility for the biochemistry faculty was also transferred. Since the original

mandate of the IMBB was as an interdepartmental graduate teaching/research institute,

these new responsibilities represented a significant expansion of that mandate. As a

result, it was deemed necessary to create an independent Biochemistry Program to

oversee the undergraduate teaching of biochemistry, and to serve as the "home

department" for biochemistry faculty. This Program was established in September of

1997. All full members of the IMBB were offered an option of primary appointment in

the new Program, or secondary appointment while retaining primary appointment in

their home Department, or Associate status while retaining sole appointment in the

home Department. In principle, faculty could choose their sole appointment in the

Biochemistry Program, but for historical reasons, and since the Program was

established largely as an undergraduate teaching program, no faculty considered this

---

option. The Director of the IMBB was appointed as the first Director of the Biochemistry

Program. ?

0

Historically, the biochemistry undergraduate program has focused on physical

biochemistry. In 1998, a proposal to introduce flexibility at the third and fourth year

levels was approved, providing two streams: Biochemistry and Molecular Biology. The

Biochemistiy Stream is

very similar to the existing Major program in biochemistry; the

new

Molecular Biology Stream

allows emphasis in molecular and cellular biology and

genetics. This expansion of the biochemistry undergraduate program will be reflected

in the 1999-2000 Calendar, and will take effect in September of 1999. The

Biochemistry Program, as presently approved, appears in Appendix 2.

The IMBB as a research institute

The IMBB was originally established as a graduate teaching and research

institute. All full members currently hold NSERC and/or MRC Research Grants. Most

of the senior members of the IMBB have served on one or more NSERC or MRC grant

selection panels: Baillie (NSERC GSC 33; MRC); Beckenbach (NSERC GSC 18;

NSERC MFA); Brandhorst (NSERC GSC 32—Chair in 95/96); Cornell (MRC); Honda

(NSERC GSC 33); Price (MRC); Smith (NSERC Genetics and Cell Biology). In 1994/95

the IMBB had members on three different NSERC Grant Selection Committees

simultaneously (Beckenbach, Brandhorst and Honda). The IMBB has a well

established national and international research reputation.

Current status of the Biochemistry Program and IMBB

At present, we have two separate entities: the

Biochemistry Program,

which

administers the undergraduate teaching program in biochemistry and molecular biology,

and the

IMBB

which has authority over the graduate program in molecular biology and

biochemistry. The faculty overlap between these programs is almost complete: of the

14 full members of the IMBB, 13 have either primary or secondary appointments in the

Biochemistry Program. In addition, two of the 13 IMBB associate members have

secondary appointments in the Biochemistry Program. All faculty holding primary

appointments in the Biochemistry Program are full members of the IMBB.

Both the IMBB and Biochemistry Program have Directors, selected in separate

nomination and election or ratification processes. To date, the same faculty member

has served as Director of both, but there is no requirement that the Biochemistry

Program and IMBB have the same Director. The Director of the Biochemistry Program

and the Director of the IMBB report to the Dean of Science in relation to personnel,

budgetary and administrative matters.

The Biochemistry Program and the IMBB share a single suite of administrative

offices, and staff. The Biochemistry Program has its own Departmental Tenure

Committee (DTC), elected by and from its members, as well as an undergraduate

(Biochemistry) Curriculum Committee (BCC). The Biochemistry DTC assesses contract

---

. ?

renewal, tenure and merit for all faculty holding primary appointments in the Program

and provides comments to the home Departments for all members holding secondary

appointments. The BCC has authority over the biochemistry undergraduate curriculum.

The Biochemistry Program also has the authority to recruit and hire faculty. The IMBB

has a Graduate Studies Committee, elected by and from its members.

In summary, the Biochemistry Program and IMBB are, at present, completely

complementary. They now have combined operating budgets, but could, in principle,

have separate Directors. The committees required to administer the two programs are

derived from overlapping, but not quite identical pools, and are elected by almost, but

not quite, identical electorate. We regard the present situation as temporary, and

extremely cumbersome. Together these two programs fulfill every requirement of a full

department: complete undergraduate and graduate degree programs; operating

budgets and administrative offices and office staff separate from any existing

department; a complete set of committees, including tenure, undergraduate and

graduate curriculum committees; the authority to recruit and fill faculty positions; and

director(s) who report directly to the Dean of Science.

Implementation

Since the teaching programs, administrative structures and facilities are already

in place, the only steps required for implementation of this proposal are the

. ?

establishment of founding faculty appointments and election of the first Chair of the

DMBB. We propose that all faculty currently holding primary or secondary

appointments in the Biochemistry Program, and any other full members of the IMBB, be

offered the option of,

(1)

sole appointment in the DMBB; (2) primary appointment in the

DMBB with a secondary appointment in another Department; (3) primary appointment

in another Department with a secondary appointment in the DMBB; or (4) no

appointment in the DMBB, but with the option of Associate status in DMBB. It is

assumed that faculty choosing sole or primary appointment in the DMBB will have their

primary teaching and service roles in the new Department. Faculty choosing secondary

appointment in the DMBB should expect to regularly participate in teaching and service

in the DMBB programs.

Faculty presently holding appointments in the Biochemistry Program or

membership in the IMBB are listed in Appendix 3. We do not anticipate that this

procedure will lead to major shifts in appointments of faculty and expect the charter

faculty complement of sole or primary appointments to be 12 - 14 faculty.

Faculty with primary appointments in other Departments whose research

interests extend to areas of molecular biology and biochemistry may supervise

graduate students in the DMBB Graduate Program if they hold a secondary

appointment.

The Chair of the DMBB shall be appointed by the standard procedure for the

election of Department Chairs.

---

Relationship of DMBB to existing Departments

Department of Chemistry

The separation of the Biochemistry Program from the Department of Chemistry

is virtually complete. Aside from shared responsibilities arising from faculty holding joint

appointments in Chemistry and Biochemistry, administrative, budgetary and academic

decisions in the Biochemistry Program reside entirely within the Program. There are no

shared teaching responsibilities for either undergraduate or graduate courses.

There are, however, significant research collaborations between members of the

Department of Chemistry and the IMBB. These collaborations should not only be

maintained, but strengthened when the status of the Biochemistry Program/IMBB is

finally resolved.

Department of Biological Sciences

The relationship between the Department of Biological Sciences and the

Biochemistry Program is complex. In addition to the joint appointments held by many

faculty, there are shared teaching responsibilities and disciplines of mutual interest.

Teaching responsibilities are currently shared between BioSciences and the

Biochemistry Program in BICH 221 (Cellular Biology and Biochemistry), BICH 222

(Molecular Biology and Biochemistry), BISC 202 (Genetics), BISC 302 (Genetic

Analysis), BISC 331 (Molecular Biology), BISC 333 (Developmental Biology), BISC 402

(Molecular Genetics), BISC 431 (Molecular Biotechnology) and BISC 453 (Advanced

Developmental Biology). These courses are commonly taught by faculty holding joint

appointments between the Biochemistry Program and BioSciences. Responsibility for

teaching these courses is handled efficiently through the cooperation of our

undergraduate curriculum committees. Any changes in these arrangements will have to

be by mutual consent of the two Departments.

We anticipate that the close relations that currently exist between the

Department of Biological Sciences and the Biochemistry Program/IMBB can, and

should, continue indefinitely after our new Department is established.

Departments of Physics and Mathematics/Statistics

Biochemical and molecular systems offer a level of complexity that is at once

approachable and challenging to physicists and mathematicians. This fact has not

been lost on either Department. One member of the Physics Department holds a

primary appointment in the Biochemistry Program (Jenifer Thewalt) and both

Departments have recently recruited faculty whose interests broadly overlap those of

the DMBB. We believe it very likely that extensive interdisciplinary ties will develop

between those departments and the DMBB.

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• ?

Financial considerations

This proposal can be implemented with little or no net cost to the University. The

Biochemistry Program/IMBB already have sufficient administrative office space and

facilities for our immediate needs. We employ an Administrative Assistant and 1.5

secretarial staff. We provide a full range of office and clerical services to our members,

including word processing, preparation of course materials, course evaluations, postal

and courier services, and telephones. The Biochemistry Program has a full time

laboratory instructor and one teaching technician. The IMBB has a part time technical

position to oversee and maintain shared equipment, including an imaging facility, with

confocal and other microscope facilities. Although we will compete with other

Departments in the Faculty of Science to maintain and expand our facilities and

services, no additional resources are necessary to form our new Department.

The Biochemistry Program/IMBB already have operating and teaching assistant

budgets. No new courses are proposed, nor are new faculty required, to implement this

proposal. The cost of any increase in enrollment in the Biochemistry program should

be managed through reallocation within the Faculty of Science, consistent with the

teaching and research activity of the members of the DMBB. We expect that any

reallocation will take into account the number of students enrolled in our courses, the

cost of mounting the courses, and the size of our B.Sc. and graduate programs,

together with the overall resources available to the Department at that time. Any

reallocation would follow the normal criteria for reallocation of resources among

Departments in the Faculty.

Since no new courses are planned, the resources of the library will continue to

be adequate. The Biochemistry Program/IMBB currently have representation on the

Faculty of Science Library Committee and the authority to advise the library on the

acquisition and cancellation of holdings. Those responsibilities will be transferred to the

DMBB.

Employment opportunities for DMBB graduands

Students choose to enroll in biochemistry and molecular biology primarily for the

employment opportunities it affords. Many of these students participate in Coop and

there are many opportunities for employment in this field. A substantial proportion of

our graduates go on to graduate or medical school. Students graduating with graduate

degrees in the MBB program have nearly all found appropriate employment. The

biotechnology, biomedical and pharmaceutical industries have been expanding at an

astonishing rate, with no end in sight. The addition of a Department dedicated to the

fields of molecular biology and biochemistry will place this Faculty, and our students, at

the forefront of these developments.

0

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Future prospects for the DMBB

The IMBB and Biochemistry Program have made extraordinary progress since

the 1984 external review. Not only have we carried out an extensive recruitment and

hiring process, but our programs were the primary impetus for the construction of the

South Sciences Building, and we are its principal occupants. The undergraduate

degree program has been expanded to include molecular biology; the graduate

program has been implemented and we now have administrative authority over those

programs. When we assumed control of the undergraduate biochemistry teaching

program in

1997,

it accounted for about 90 FTE. That number has now increased to

over 130. The Biochemistry Program graduated 33 students in 97/98, and has

consistently been the third largest program in the Faculty of Science in numbers of

Majors, Honors and graduands.

.

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Appendix 1

Graduate Program?

1998-1999 Calendar Entry

IMBB

have appointments in the Biochemistry Program, and/or Departments of Biological Sciences,

Chemistry and Physics. In addition, the

IMBB

has associate members who may also serve as senior

supervisors for students in the MBB graduate program.

Information about the Molecular Biology and Biochemistry program, and the research activities of its

faculty, can be obtained from the MBB graduate secretary, Institute of Molecular Biology and

Biochemistry, Simon Fraser University, 8888 University Drive, Burnaby,

BC,

V5A 1S6. Telephone

(604) 291-5630

Admission

For admission requirements, refer to the

Graduate General Regulations.

Applicants should normally

have completed some advanced course work in biology or biochemistry.

Degree Requirements

All students will be assigned a graduate supervisory committee which has the authority to specify an

appropriate program of course work meeting or exceeding the minimum requirements stated below.

All students are expected to attend the

IMBB

research seminar series and to participate regularly in a

journal club.

MSc Program

Course Work

The minimum requirements consist of 12 credit hours of graduate course credits including MBB 801 and

802.

Research

A major part of the MSc program will be devoted to original research. A thesis describing the work must

be submitted and defended in accordance with

Graduate General Regulations.

PhD Program

Course Work

For students entering the program with a BSc or equivalent, a minimum of 20 credit hours of credit is

required,. at least 15 of which must be at the graduate level, including MBB 801, 802 and 806. PhD

students must normally enroll in MBB 806 at the earliest opportunity following four semesters of

registration in the program. With the approval of their supervisory committee, students in the MSc

program may apply to the MBB graduate program committee for transfer to the PhD program.

For students entering the program with an MSc degree, eight credit hours of credit is required, at least six

of which must be at the graduate level, including MBB 802 and 806. The latter course must be taken at

the first opportunity following two semesters of registration in the program.

Research ?

0

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.

The major portion of the PhD program will be devoted to original research. An original thesis, which

contributes to new knowledge, must be presented and defended at the end of the degree program, in

accordance with the

Graduate General Regulations.

In addition, all NOB PhD candidates must present a

public seminar on their research.

Courses Offered by Other Departments

The following relevant courses are offered by other departments: CHEM

752, 754

and 811.

Graduate Course Work at Other Universities

Upon the recommendation of the supervisory committee, and with the approval of the graduate program

committee, up to six credits of course work taken elsewhere not resulting in a degree may be applied

toward degree requirements, but not exceeding more than half of the credits required in addition to MBB

801, 802 and 806.

Graduate Courses

MBB 801-2 Student Seminar in Molecular Biology and Biochemistry I

Discussion of recent literature through student seminars and written reports. Cannot be taken for credit in

addition to CHEM 801

MBB

802-2

Student Seminar in Molecular Biology and Biochemistry II

Discussion of recent literature through student seminars and written reports. Prerequisite: MBB 801 or an

MSc degree. Cannot be taken for credit in addition to CHEM 802.

MBB 806-3 Ph.D. Graduate Research Seminar

Oral presentation and defense of a written Ph.D. research proposal. Students will be examined on their

progress and grasp of knowledge relevant to the proposed research and their capacity to complete the

proposed thesis research. Open only to students in the molecular biology and biochemistry graduate

program. Cannot be taken for credit in addition to CHEM 806.

MBB 811-1, MEB 812-2, MBB 813-3 Techniques in Molecular Biology and Biochemistry

Consideration of methods applied to research in molecular, cellular, and developmental biology; genetics;

and biochemistry. Can be repeated with permission of the instructor.

MBB 821-3 Nucleic Acids

An examination of recent literature for revelations about the structure and function of DNA and RNA.

MBB 822-3 Biological Membranes

A review of recent literature on the structure, dynamics, function, and biosynthesis of membrane lipids

and proteins.

MBB 823-3 Protein Structure and Function

.

Transition state theory; specificity in enzyme catalyzed reactions; use of recombinant DNA techniques to

describe and modify enzyme catalysis, catalytic activities through monoclonal antibody techniques.

---

4

MBB 824-3 Physical Biochemistry

The physical properties of biomacromolecules; modern physical methods applied to biomolecules;

properties and analysis of membrane systems.

MBB 825-3 Bioenergetics

Consideration of important processes for biological energy transduction. Structure/function relationships

of membrane components and other interacting macromolecular systems. Cannot be taken for credit in

addition to CHEM 825.

MBB 826-3 Molecular Immunology

An overview of cellular and humoral immunology with emphasis on the molecular basis of immune

recognition and response.

MBB 827-3 Mechanisms in Enzyme Catalysis

The study of enzyme mechanisms by a variety of techniques including spectroscopic, kinetic,

radioisotopic exchange, site-directed mutagenesis.

MIBB 828-3 Spectroscopic Methods in Biochemistry

Application of spectroscopic methods including multidimensional NMR, fluorescence, circular dichroism,

and FTIR for determination of biomacromolecular structure. Includes elements of protein conformation.

Cannot be taken for credit in addition to CHEM 828.

MBB 829-3 Special Topics in Biochemistry

Consideration of recent literature concerning selected contemporary research topics. Can be taken more

than once with permission of the instructor.

MBB 831-3 Molecular Evolution of Eukaryote Genomes

Examination of the dynamics of change in eukaryotic nuclear, mitochondrial, and chioroplast genome

structure and organization.

MBB 832-3 Molecular Phylogeny and Evolution

Examination of the basic methods applicable to analyses of molecular phylogeny and evolution.

NOB 833-3 Developmental Genetics

Selected topics on the developmental genetics of drosophila.

MBB 834-3 Topics in Developmental Biology

Selected topics including pattern formation, morphogenetic determinants, inductive interactions, and

differential gene expression in embryos.

MBB 835-3 Genomic Analysis

Consideration of topics related to the structure and function of the genome with emphasis on genome

mapping and sequencing projects, and computational methods for genomic sequence analysis.

MBB 836-3 Gene Expression

A consideration of the mechanisms and regulation of gene expression in eukaryotes and prokaryotes.

MBB 837-3 Molecular Genetics of Signal Transduction

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5

•

Consideration of mechanisms of signal transduction using molecular genetic approaches with emphasis

on the yeast Saccharomyces cerevisiae. Cannot be taken in addition to BISC 861.

MIBB

839-3

Special Topics in Molecular Biology

Consideration of recent literature concerning selected contemporary research topics. Can be taken more

than once with permission of the instructor.

MBB

871-1

Directed Readings in Molecular Biology and Biochemistry.

Programs of directed reading and critical discussions offered by staff members to individual students

according to their needs. Study programs must be approved by the molecular biology and biochemistry

program committee.

MBB

872-2

Directed Readings in Molecular Biology and Biochemistry.

Programs of directed reading and critical discussions offered by staff members to individual students

according to their needs. Study programs must be approved by the molecular biology and biochemistry

program committee.

MBB

873-3

Directed Readings in Molecular Biology and Biochemistry.

Programs of directed reading and critical discussions offered by staff members to individual students

according to their needs. Study programs must be approved by the molecular biology and biochemistry

program committee.

MBB

898

M.Sc. Thesis

I*

MBB

899

Ph.D. Thesis

0

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Appendix

2

Present Undergraduate Program?

1999-2000 Calendar Entry

Biochemistry Program

Students who have already declared majors or honors in the Biochemistry Program may follow the program

requirements in effect when they were accepted into the program, or the program requirements as set Out

below, whichever is to their advantage.

Major Program

(120 semester hours)

All students must complete the lower and upper division cores plus additional courses as specified in either

the Molecular Biology or Biochemistry Stream as indicated below.

Lower Division Core

(52-53

semester hours)

BICH 221-3 Cell Biology and Biochemistry

BICH 222-3 Molecular Biology and Biochemistry

BISC 101-4 General Biology

BISC 102-4 General Biology

BISC 202-3 Genetics

CHEM 121-4 General Chemistry and Laboratory I

CHEM 122-2 General Chemistry H

CHEM 126-2 General Chemistry Laboratory

II

CHEM 215-4 Introduction to Analytical Chemistry

CHEM 281-4 Organic Chemistry and Laboratory I

CHEM 282-2 Organic Chemistry

II

CHEM 286-2 Organic Chemistry Laboratory II

one of

CMPT 101-4 Introduction to Computer Programming

CMPT 102-3 Introduction to Scientific Computer Programming

CMPT 110-3 Event-Driven Programming in Visual Basic

one of

MATH 151-3 Calculus I

MATH

154-3

Calculus I for the Biological Sciences*

one of

MATH 152-3 Calculus II

MATH 15

5-3

Calculus II for the Biological Sciences*

one of

PHYS 120-3 Modem Physics and Mechanics

PHYS 101-3 General Physics I

one of

PHYS 121-3 Optics, Electricity and Magnetism

PHYS 102-3 General Physics II

?

4D

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2

• ?

Recommended Course

MATH 251-3 Calculus III

*Note: Course alternatives marked with an asterisk are possible only for students who have transferred to

Biochemistry from another program. Students who have declared (or intend to declare) a major or honors

program in Biochemistry should not register for these alternative courses.

Upper Division Core

(22-23 semester hours)

BICH 311-2 Analytical Biochemistry Laboratory

BICH 312-2 Metabolism Laboratory

BICH 321-3 Intermediary Metabolism

BICH 322-3 Molecular Physiology

BISC 331-3 Molecular Biology

CI{EM 360-3 Chemical Kinetics and Thermodynamics

one of

BISC 431-4 Molecular Biotechnology

BISC

457-3

Plant Molecular Biology and Biotechnology

one of

MATH 310-3 Introduction to Ordinary Differential Equations

STAT 302-3 Analysis of Experimental and Observational Data

• ?

Upper Division Streams

In addition to the lower and upper division cores, students must complete all

of the requirements in one of

the two streams listed below:

Molecular Biology Stream

(15-18 semester hours)

two courses from

BICH 403-3 Physical Biochemistry

BICH 412-4 Enzymology

BICH 421-3 Nucleic Acids

BICH 422-3 Biornembranes

BICH 423-3 Protein Structure and Function

BICH 426-3 Immunology

plus one course'from

BISC 302-3 Genetic Analysis

BISC 303-3 Microbiology

BISC 405-3 Cell Physiology

plus one course from

BISC 333-3 Developmental Biology

BISC 402-3 Molecular Genetics

BICH 435-3 Genomic Analysis

plus one course from

. ?

BISC 305-3 Animal Physiology

?

BISC 400-3 Evolution

---

BISC

453-3

Advanced Developmental Biology

BISC 439-3 Industrial Microbiology

BICH 491-5 Undergraduate Research

or with permission of the undergraduate advisor

another 400-level BICH course

BISC 471-3 Special Topics in Biology

BISC 472-3 Special Topics in Biology

BISC 473-3 Special Topics in Biology

Biochemistry Stream

(15-17 semester hours)

BICH 403-3 Physical Biochemistry

BICH 412-4 Enzymology

BICH 413-2 Physical Biochemistry Laboratory

plus two courses from

BICH 420-3 Selected Topics in Contemporary Biochemistry

BICH 421-3 Nucleic Acids

BICH 422-3 Biomembranes

BICH 423-3 Protein Structure and Function

BICH 426-3 Immunology

BICH 49

1-5

Undergraduate Research

CHEM 333-3 Inorganic Chemistry of Biological Processes

In addition to the above requirements, students majoring in Biochemistry must complete 26-31 semester

hours of electives, with enough upper division credits to bring the total of the latter to 44 semester hours.

Students must have a total of 12 semester hours taken in subjects outside the Faculty of Science (excluding

EDUC 401 to 407), including a minimum of 6 hours from the Faculty of Arts. Further BSc general degree

regulations are given in the Faculty of Science section.

Although many variations are possible, a student entering with BC High School Chemistry 12, Mathematics

12 and Physics 12 (or equivalents) might take the following typical program.

Levels 1 and 2

BISC 101-4 & 102-4

CHEM 121-4, 122-2 & 2814

MATH 151-3 & 152-3

PHYS 120-3 & 121-3

Levels 3 and 4

BICH 221-3 & 222-3

BISC 202-3

CHEM 126-2, 282-2, 286-2 & 215-4

CMPT 101-4, 102-3, or 110-3

6 hours of electives

hours

Levels

5

and 6

BICH311-2, 312-2, 321-3 & 322-3

BISC 331-3 & 431-4 or 457-3

Total 30 semester hours

Total 28-29 semester

.

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4

CHEM 360-3

MATH 310-3 or STAT 302-3

9 hours of electives

hours

Levels 7 and 8

Requirements of one of the streams (15-18 hours)

11-16 hours of electives

Total 31-32 semester

Total 29-31 semester hours

Honors Program

(132 semester hours)

In addition to the requirements shown above for the major program, students taking honors in Biochemistry

must complete one of the following Individual Study Semester Options:

either BICH 493-15 Individual Study Semester (Option B)

or BICH 49

1-5

Undergraduate Research plus BICH 492-10 Individual Study Semester (Option A)*

*This may be accomplished by breaking the individual study semester project into two consecutive

semesters (cf. criteria for approval of individual study semesters on p._ of the Calendar). If BICH 491-5

has already been taken to satisfy the major program requirements, then the student must complete one other

course selected from the appropriate list in either the Molecular Biology or Biochemistry Stream in addition

to BICH 492-10 in order to satisfy the honors requirements. Students must have a total of 12 semester hours

taken in subjects outside the Faculty of Science (including 6 hours in the Faculty of Arts but excluding

EDUC 401 to 407); and sufficient upper division courses to bring the total number of upper division credits

• ?

to at least 60 semester hours. Further BSc Honors requirements are given in the Faculty of Science section.

Minor Program

(56-60 semester hours minimum)

Lower Division Requirements

(42 semester hours minimum)

BICH 221-3 Cell Biology and Biochemistry

BICH 222-3 Molecular Biology and Biochemistry

BISC 101-4 General Biology

BISC 102-4 General Biology

CHEM 1214 General Chemistry and Laboratory I

CHEM 122-2 General Chemistry II

CHEM 126-2 General Chemistry Laboratory H

CHEM 2814 Organic Chemistry and Laboratory I

CHEM 282-2 Organic Chemistry II

CHEM 286-2 Organic Chemistry Laboratory H

one of

MATH 151-3 Calculus I

MATH 154-3 Calculus I for the Biological Sciences

one of

MATH 152-3 Calculus II

MATH

155-3

Calculus II for the Biological Sciences

one of

---

PHYS 120-3 Modem Physics and Mechanics

PHYS 101-3 General Physics I

one of

PHYS 121-3 Optics, Electricity and Magnetism

PHYS 102-3 General Physics II

Upper Division Courses

(14-18 semester hours)

Students must complete five upper division courses (plus any lower division prerequisites) with a minimum

of 14 semester hours selected from:

Any upper division BICH course (excluding BICH 492-10 and 493-15)

BISC 331-3 Molecular Biology

one of

BISC 431-4 Molecular Biotechnology

BISC

45

7-3 Plant Molecular Biology and Biotechnology

S

0

---

Appendix 3

.

.

S

Potential Pool of Faculty for the DMBB

Current Appointments

Faculty Member

?

Rank

?

Primary

?

Secondary ?

IMBB Status

Baillie, D.L.

Professor

Biochemistry

Biosciences

Full

Beckenbach, A.T

Assoc. Professor

Biosciences

Biochemistry

Full

Borgford, T.J.

Assoc. Professor

Biochemistry

Chemistry

Full

Brandhorst, B. P.

Professor

Biochemistry

Biosciences

Full

Cornell, R.B.

Professor

Biochemistry

Chemistry

Full

Cushley, R.J.

Professor

Biochemistry

Chemistry

Full

Davidson, W.

Professor

Biochemistry

-

Harden, N.

Asst. Professor

Biochemistry

Biosciences

Full

Honda, B.M.

Assoc. Professor

Biosciences

Biochemistry

Full

Price, J.V.

Assoc. Professor

Biochemistry

Biosciences

Full

Richards, W.R.

Professor

Biochemistry

Chemistry

Full

Scott, J.K.

Assoc. Professor

Biochemistry

Biosciences

Full

Sen, D.

Assoc. Professor

Biochemistry

Chemistry

Full

Smith, M.J.

Professor

Biosciences

-

Full

Thewalt, J.L.

Asst. Professor

Biochemistry

Physics

Full

Bennet, A.J.

Assoc. Professor

Chemistry

-

Associate

Breden, F.

Assoc. Professor

Biosciences

-

Associate

Burr, A.H.

Assoc. Professor

Biosciences

-

Associate

Crespi, B.J.

Assoc. Professor

Biosciences

-

Associate

Druehl, L.D.

Professor

Biosciences

-

Associate

1-launerland, N.H.

Assoc. Professor

Biosciences

-

Associate

Kafer, E.

Adjunct Prof.

Biochemistry

-

Associate

Kermode, A.R.

Assoc. Professor

Biosciences

-

Associate

Moore, M.M.

Assoc. Professor

Biosciences

-

Associate

Pinto, B.M.

Professor

Chemistry

-

Associate

Plant, A.L.

Asst. Professor

Biosciences

-

Associate

Tibbits, G.F.

Professor

Kinesiology

Biochemistry*

Associate

Tracey, A.S.

Adjunct Prof.

Chemistry

Associate

* Approved for Secondary Appointment in the Biochemistry Program.